a4b7 Integrin peptidomimetic antagonistKessler, H
Jovani M, Danese S. Vedolizumab for the treatment of IBD: a selective therapeutic approach targeting pathogenic a4b7 cells. Curr Drug Targets. 2013 Nov;14(12):1433-43. doi: 10.2174/13894501113146660206. PMID: 23980911
靶点别称:Integrin alpha 4 beta 7,Integrinα4β7,Integrina4b7 物种:Human 属性:Protein 标记:Unconjugated 蛋白结构(Molecular Characterization) Human ITGA4&ITGB7 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA4 and ITGB7, has a calculated MW of 111.4 kDa (ITGA4) & 83...
抗a4B7整合素(Vedolizumab),人源化抗体又称Anti-a4B7 Integrin (Vedolizumab), Humanized Antibody该产品是Biovision品牌提供的抗体,艾美捷科技作为中国区域代理商提供原装进口产品,并且有独立的产品技术支持人员答疑解惑,售后一直广受老师和学生的好评。为您提供及时的咨询响应,专业的产品和解决方案支持,稳健快捷的交货周期...
上海玉博生物科技有限公司 主要致力于“anti-mouse LPAM-1 (Integrin a4b7) PE DATK32 (DATK-32) 200 ug eBioscience-12-5887-83”的生产销售。多年的“anti-mouse LPAM-1 (Integrin a4b7) PE DATK32 (DATK-32) 200 ug eBioscience-12-5887-83”生产与销售的经验,与各行业
NUCLEIC ACIDS ENCODING HUMANIZED IMMUNOGLOBULIN THAT BINDS A4B7 INTEGRINLI, PingGraf, Marcus
A cation π-interaction regulates ligand binding affinity and signaling of integrin a4b7 Cation-π interaction regulates ligand-binding affinity and signaling of integrin α4β7. Proc Natl Acad Sci USA. 2010; 107 :21388–93. doi: 10.1073/pnas.1015487107. [ Cross Ref ]Pan Y, Zhang K, Qi J...
Chen YB, McDonough S, Chen H, Chen H, Coughlin E, Illiano Cet al. Expression of a4b7 Integrin on peripheral blood memory CD4+T-cells after allogeneic HCT correlates with non-relapse mortality and overall survival.Biol Blood Marrow Transplant2012;18: S334. ...
2014. Targeting a4b7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut- associated lymphoid tissue from infection. Nat. Med. 20: 1397-1400.Byrareddy, S.N. et al. Targeting a4b7 integrin reduces mucosal transmis- sion of simian immunodeficiency virus and ...
(1998) MAdCAM-1 costimulates T cell proliferation exclusively through integrin a4b7, whereas VCAM-1 and CS-1 peptide use a4b1: Evidence for ``remote'' costimulation and induction of hyperresponsiveness to B7 molecules. Eur J Immunol 28: 3605聴3615....