Meta-omics technologies, alongside environmental measurements, allow researchers to infer the complex network of a microbiome and its relations with the environment and host, offering a putative picture of their metabolism in their natural habitat [11, 12]. With metagenomics, we analyse the total DNA...
Here, we describe a technological workflow for facilitating ELMs design by rationally integrating bioinformatics, structural biology and synthetic biology technologies. We first develop bioinformatics software, termed Bacteria Biopolymer Sniffer (BBSniffer), that allows fast mining of biopolymers and biopolymer...
Integrative analysis defined disease-relevant CCANs in multiple cell subtypes and discovered LOAD-associated cell subtype-specific candidatecisregulatory elements (cCREs), their candidate target genes, andtrans-interacting transcription factors (TFs), some of which, includingELK1,JUN,andSMAD4in excitatory...
DNA methylation, the first layer of epigenetic regulation, is causally implicated in human obesity and T2D through diverse aetiological pathways7,8,9. These pathways include in utero programming of disease risk, long-term effects of diet and lifestyle, mediation of causal genetic variations, age-re...
In: Information and communication technologies in public administration: innovations from developed countries. CRC, London, pp 275–298 Google Scholar Schüngel M, Stackebrandt E, Bizet C, Smith D (2013) MIRRI—the microbial resource research infrastructure: managing resources for the bio-economy....
Strategic intelligence on emerging technologies: Scientometric overlay mapping Given the flexibility (i.e., adaptability to different sources of data) and granularity (i.e., applicability across multiple levels of data aggregation) ... D Rotolo,I Rafols,MM Hopkins,... - 《Journal of the Associati...
Decisions are made under the guidance of management techniques while information technologies assist the implementation. Under the context of intense competition, decision-making requires not only the knowledge and experience of managers but also the technological platforms to collect data, process ...
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Programming a healthier future Bhushan Patwardhan, ... Sarika Chaturvedi January–February 2025View PDF Research articleOpen access Molecular dynamics directed neuroprotective activity of alcoholic extract ofGaruga pinnataRoxb. in experimental rats
Advances in DNA sequencing technologies have revolutionised rare disease diagnostics and have led to a dramatic increase in the volume of available genomic data. A key challenge that needs to be overcome to realise the full potential of these technologie