Here, we describe a technological workflow for facilitating ELMs design by rationally integrating bioinformatics, structural biology and synthetic biology technologies. We first develop bioinformatics software, termed Bacteria Biopolymer Sniffer (BBSniffer), that allows fast mining of biopolymers and biopolymer...
In: Information and communication technologies in public administration: innovations from developed countries. CRC, London, pp 275–298 Google Scholar Schüngel M, Stackebrandt E, Bizet C, Smith D (2013) MIRRI—the microbial resource research infrastructure: managing resources for the bio-economy....
Meta-omics technologies, alongside environmental measurements, allow researchers to infer the complex network of a microbiome and its relations with the environment and host, offering a putative picture of their metabolism in their natural habitat [11, 12]. With metagenomics, we analyse the total DNA...
instruments, databases, and materials utilized to create the model. They outline what VS is and how crucial it is to the process of finding new drugs. Good points for this study, they highlighted the DL technologies that are accessible as open access programming libraries...
Advances in multi-omics technologies enable us to access multi-layer information from the genome, transcriptome, proteome, metabolome, and epigenome, fueling the development of cancer precision medicine [4]. The Cancer Genome Atlas (TCGA) is one of the largest collections of multi-omics data ...
However, carcass merit traits are expressed late in life and the measurement of these traits for individual live animals is relatively expensive via ultrasound technologies. In many cases evaluation occurs post mortem, thereby eliminating breeding stock with superior breeding values for the traits. The...
HTS technologies are frequently used to investigate biological phenomena on a genomic scale. Unfortunately, the big data generated are often underutilized when experimental biologists run into programming roadblocks. When handling large data files generated by HTS, we often run across difficulties. For ...
Strategic intelligence on emerging technologies: Scientometric overlay mapping Given the flexibility (i.e., adaptability to different sources of data) and granularity (i.e., applicability across multiple levels of data aggregation) ... D Rotolo,I Rafols,MM Hopkins,... - 《Journal of the Associati...
DNA methylation, the first layer of epigenetic regulation, is causally implicated in human obesity and T2D through diverse aetiological pathways7,8,9. These pathways include in utero programming of disease risk, long-term effects of diet and lifestyle, mediation of causal genetic variations, age-re...
Advances in DNA sequencing technologies have revolutionised rare disease diagnostics and have led to a dramatic increase in the volume of available genomic data. A key challenge that needs to be overcome to realise the full potential of these technologie