Energy metabolism 1. Introduction Short-chain chlorinated paraffins (SCCPs) are mixtures of polychlorinated n-alkanes with 10–13 carbon atoms. As a constituent of chlorinated paraffins, SCCPs are widely used in various industrial applications, including plasticizers, flame retardants, metal-working flui...
These studies have identified many N-responsive transcripts that are associated with the above processes, but many genes with unknown effects are also involved in aspects of plant metabolism under conditions of low N stress. Wild germplasm resources in plants are important in the field of botany. ...
These approaches include Gene Inactivity Moderated by Metabolism and Expression (GIMME)37, integrative metabolic analysis tool (iMAT)38, Metabolic Adjustment by Differential Expression (MADE)39, E-flux40 and Probabilistic Regulation of Metabolism (PROM)41. The GIMME and iMAT use gene expression data ...
Background: Genome-wide transcript profiling and analyses of enzyme activities from central carbon and nitrogen metabolism show that transcript levels undergo marked and rapid changes during diurnal cycles and after transfer to darkness, whereas changes in activities are smaller and delayed. In the ...
From DNA binding to meta- bolic control: integration of -omics data reveals drug targets for prostate cancer. EMBO J 2011;30:2516-7.H. Gao and K. Dahlman-Wright, "From DNA binding to meta- bolic control: integration of-omics data reveals drug targets for prostate cancer," EMBO Journal,...
Module 3 contained genes involved in lipid metabolism, and module 7 contained genes associated with adipocytokine and insulin signaling processes. The Wnt pathway is associated with module 6, while the MAPK pathway is associated with module 4 and 5 (Table 3 and Additional file 1). Figure 4 A...
In response to treatment with a fungal elicitor, the biosynthesis and accumulation of sanguinarine is induced along with other plant defense responses in opium poppy cell cultures. The transcriptional induction of alkaloid metabolism in cultured cells provides an opportunity to identify components of this...
metabolismtoxicologyfunctional genomicsmolecular biological toolsapplication of toxicogenomicsmechanism of bromobenzene‐induced hepatotoxicityWilbert H. M. HeijneTNO Food and Nutrition Research, Department of Explanatory Toxicology, Utrechtseweg 48, P.O. Box 360, 3600 AJ Zeist, The NetherlandsBen van Om...
In contrast, Clone A (C2) comprised molecular signatures, such as oxidative phosphorylation, DNA repair, and fatty acid metabolism. Thus, the distribution of clustered cells showed differential characteristics within intratumoral heterogeneity. Collectively, these data indicated that a specific VAV1 ...
Yaping Shao1, Min Yan1, Xinjie Zhao1,Yinghao Sun2 & Guowang Xu1 In-depth delineation of lipid metabolism in prostate cancer (PCa) is significant to open new insights into prostate tumorigenesis and progression, and provide potential biomarkers with greater accuracy for improved ...