This is automatically derived from the IntAct database and is updated on a triweekly basis. Interactions can be derived by any appropriate experimental method but must be confirmed by a second interaction if re
IntAct是由欧洲生物信息研究所（EMBL-EBI）维护的开源分子相互作用数据库，专注于蛋白质、核酸等生物分子相互作用数据的存储、分析与共享。其数据通过文献人工提取和用户直接提交两种方式获取，截至2025年已收录超过58,000条人工标注的分子相互作用注释数据。该平台支持多物种研究，涵盖人类、小鼠等模式生物，并提供DNA 蛋白...
蛋白质相互作用的数据库非常的多,比如DIP, MINT, IntAct, BioGRID等,不同数据库中的信息存在了大量的冗余,而且在不同数据库之间进行检索也非常的费力。 为了减少不同数据库的冗余,最大化提升数据存储和检索的效率,由多个数据库的开发团队和维护者共同参与成立了一个委员会,名字叫做international molecular exchange c...
The IntAct molecular interaction database in 2012Transformation of intact yeast cells treated with alkali cations.Transformation of intact cells treated with alkali cations. J BacteriolMethod for the isolation of intact islets of Langerhans from the rat pancreas.Studies on the transformation of intact ye...
The IntAct molecular interaction database in 2012 Transformation of intact yeast cells treated with alkali cations. Transformation of intact cells treated with alkali cations. J Bacteriol Method for the isolation of intact islets of Langerhans from the rat pancreas. ...
PPI database:STRING VS IntAct VS IMEx 技术标签:计算生物学习笔记 S. Orchard et al., “Protein interaction data curation: The International Molecular Exchange (IMEx) consortium,” Nature Methods, vol. 9, no. 4, pp. 345-350, Apr 2012 Henning et al, IntAct: ......
Analysis of therapeutic antibody subunits facilitates exact molecular weight analysis of their heavy and light chains and further top down analysis can provide sequence confirmation. Protein analysis in native or native-like conditions decreases charge...
Data were presented as mean ± SD (n = 3). Boxes below the chart indicated the genetic alterations in ESCC cells (M, mutation; Red, amplification; Blue, copy number loss; Grey, no data). Genetic alterations were obtained from CCLE database (https://sites.broadinstitute.org/ccle/). b,...
Our findings provide the molecular basis for direct, antibody-like αβTCR recognition of an intact protein, PE, in the absence of antigen-presenting molecules. Using a broad range of cellular and biophysical assays we validated the specificity of this interaction and determined the crystal structure...
To uncover the changes in the 3D structure of brain proteins corresponding human homologs, we focused on 780 proteins known to be expressed in the brain based on the Human Protein Atlas database (https://www.proteinatlas.org) and also found to be dimethyl-labeled in our brain dataset. To ...