Insulin-producing cells containing insulin-positive and NKX6.1-positive cells in a proportion of 30% or more and insulin-positive and NKX6.1-negative cells in a proportion of more than 15%.伊藤 亮山添 則子日吉 秀行持田 泰佑上野 光
电子邮件地址michael.kung@139.com Latest from 伤口世界 A prenatal skin atlas reveals immune regulation of human skin morphogenesis(2) A prenatal skin atlas reveals immune regulation of human skin morphogenesis(1) Multiscale spatial mapping of cell populations across anatomical sites in healthy...
The purpose of the present invention is to provide a novel method for making it possible to efficiently induce/produce endocrine cells from pluripotent stem cells. Insulin-producing cells including cells that are insulin-positive and NKX6.1-positive in a ratio of at least 30%, and cells that ar...
专利名称:INSULIN-PRODUCING CELLS 发明人:ITO, Ryo,伊藤亮,KONAGAYA, Shuhei,小長谷周 平,YAMAZOE, Noriko,山添則子,HIYOSHI, Hideyuki,日吉秀行,MOCHIDA, Taisuke,持田泰 佑,UENO, Hikaru,上野光,SAKUMA, Kensuke,佐 久間健介,YAMAURA, Junji,山浦順 司,MATSUMOTO, Hirokazu,松本寛 和,TOYODA, Taro,豊田...
Mesenchymal stromal cells (MSCs) can be obtained from various tissues for differentiation into insulin-producing cells (IPCs) [34,61,69,72,77]. The adipose tissue offers distinct advantages due to its availability and significant therapeutic potential, characterized by its intrinsic regenerative ...
After being infected with Ad-PDX-1, hMSCs were successfully induced to differentiate into insulin-secreting cells. The differentiated PDX-1+ hMSCs expressed multiple islet-cell genes including neurogenin3 (Ngn3), insulin, GK, Glut2, and glucagon, produced and released insulin/C-peptide in a ...
RESEARCH HIGHLIGHTS Nature Reviews Molecular Cell Biology | AOP, published online 12 November 2014; doi:10.1038/nrm3907 PhotoDisc/Getty Images STEM CELLS Insulin-producing β-cells in a dish Human pluripotent stem cells can potentially generate cells and tissues that could be used for the treatment ...
(Fig.1C,J). An MSC-related surface marker analysis by flow cytometry showed that both cells contained high proportion of Cd90+cells, while the proportion of Cd73+cells was relatively low. The expression of the hematopoietic surface marker (Cd45) was considered absent in both cells (Fig.1D...
People living with diabetes might have a new hope. Scientists have tested a new drug therapy in diabetic mice, and found that it boosted insulin-producing cells by 700% over three months, effectively reversing their disease. Beta cells in the pancreas have the important job of producing insulin...
6) insulin-producing cells 胰岛素分泌细胞 1. Role of pancreatic duodenal homeobox gene-1 in committed-differentiation of bone marrow mesenchymal stem cells intoinsulin-producing cells; 胰腺十二指肠同源框1基因在大鼠骨髓间充质干细胞向胰岛素分泌细胞定向分化过程中的作用 ...