胰岛素样生长因子1(Insulin-like growth factor 1,IGF-1)也被称为生长调节素C(somatomedin C),是一组具有促生长作用的多肽类物质,胰岛素样生长因子(IGF-1),由70个氨基酸组成,分子量7649 Da,结构有45%与胰岛素相似。IGF-1的重要作用之一是介导GH在外周靶器官组织的促生长效应,其促进增殖作用是胰岛素的50倍左右,...
IGF 英文缩写IGF 英文全称Insulin-like Growth Factor 中文解释胰岛素样生长因子 缩写简介 在胚胎发育和出生后的生长生理中起关键作用的肽类激素。IGF-I和IGF-Ⅱ既能起循环内分泌激素的作用,也能作为有旁分泌和自分泌作用的局部产生的生长因子。它们除了在正常组织中广泛地表达外,也有在广谱的癌细胞类型中检测到。
Insulin-like growth factor (IGF) molecules form part of an axis, which includes (IGF-I and IGF-II), the two cell surface receptors (IGF-IR and IGF-IIR), a family of IGF binding proteins (IGFBP-1 to IGFBP-6), and proteases. IGF-I has been known to shape the cochlea, whereas IGF...
Insulin-Like Growth FactorII (33-40) 编号:120107 CAS号: 三字母:H2N-Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg-OH 描述: 留言 收藏 Insulin-Like Growth FactorII (69-84) 编号:172726 CAS号: 三字母:H2N-Asp-Val-Ser-Thr-Pro-Pro-Thr-Val-Leu-Pro-Asp-Asn-Phe-Pro-Arg-Tyr-OH 描述: ...
IGF- I, dependent on GH, can promote proliferation of many cells in vitro and promote protein and DNA synthesis. Many tissues and cells in the body can autocrine and paracrine IGF- I. IGF- II, known as the major growth factor before birth, does not require growth hormone regulation and ...
similar,insulin-likegrowthfactorIandII(IGFI,II)to emphasizetheirhomologywithinsulinstructure.Itwasalso confirmedthatthesulfationfactorandtheproliferation stimulatingactivityweremembersofthesamepolypeptide familyasIGF. Composition,physicalandchemicalpropertiesofIGFssystem ...
Insulin-Like Growth Factor (IGF-I) in Mauriac Syndrome or Diabetic Dwarfism Turkish Journal of Medical SciencesSimsek, EnverKocabay, Kenan
With the development of molecular biology, 1978 people purified two kinds of NSILA (I, II) and found its structure and proinsulin were named as similar, insulin-like growth factor I and II (IGF I, II) to emphasize their homology with insulin structure. It was also confirmed that the ...
MCE 国际站:Insulin-like Growth Factor 1 Receptor 品牌:MedChemExpress (MCE) 概述:胰岛素样生长因子 (IGF) 系统包括两个主要受体IGF-IR 和 IGF-IIR。IGF-IR 和IGF-IIR 都是结构和功能完全不同的跨膜糖蛋白。IGF-IR 是由两个相同的 α 亚基和两个相同的 β 亚基组成的四聚体。在结构上,IGF-IR 与胰岛...
胰岛索样生长因子一1(Insulin—like Growth Factor—l,IGF 1)是胰岛素样生长因子的重要成员,与胰岛索高度同源.这个系统的其它成员还包括IGF Ⅱ、1GF—l受体(IGFIR)、IGF Ⅱ受体(IGFIIR)以及4种胰岛素生长因子结合蛋白(IGF BP-1、-2、-3、-4).其中胰岛素样生长因子-1(Insulin-like growth factor-1,IGF-1)...