胰岛素分泌模式调节剂(insulin secretion pattern regulators) 相关知识点: 试题来源: 解析 对胰岛K+-ATP通道具有“快开”和“快闭”作用,显著较其他口服降糖药起效迅速,作用时间短,使胰岛素的分泌达到模拟人体生理模式——餐时胰岛素迅速升高,餐后及时回落到基础分泌状态。亦称为餐时血糖调节剂。
网络释义 1. 胰岛素分泌 is是什么意思_... ... [=insertion sequences] 插入序列 [=insulin secretion]胰岛素分泌[=intercellular space] 细胞间隙 ... zh-cn.oldict.com|基于24个网页 2. 胰岛素释放 胰岛素释... ... ) Ratio of insulin to glucose 胰岛素释放指数 )insulin secretion胰岛素释放) Insulin...
Insulin SecretionFesta, AndreasHanley, Anthony J GTracy, Russell PAgostino, Ralph DHaffner, Steven M
f, Glucose-stimulated insulin secretion of antral GINS organoids at different time points (days post differentiation) or from different batches. n=4 independent groups of GINS organoids for the time course GSIS. n=5 independent groups of GINS organoids for batch 1, n=4 independent groups of ...
Prentki M, Matschinsky FM: Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion.Physiol Rev67:1185–1248, 1987. Google Scholar Turk J, Wolf BA, McDaniel ML: The role of phospholipid-derived mediators including arachidonic acid, its metabolites, and inositol...
It has long been accepted wisdom that insulin secreted from islet β cells has either no effect, or an inhibitory feedback effect, on insulin synthesis and secretion. Recent work suggests, instead, that secreted insulin acts directly on β cells, via its own receptor, to enhance insulin product...
One such function is the glucose-stimulated insulin secretion (GSIS) by pancreatic β-cells that is central to blood glucose homeostasis. Aberrant insulin production is a hallmark of diabetes resulting from autoimmune destruction of β-cells (type 1 diabetes; T1D) or hormone resistance by tissues ...
Effects of islet hormones on insulin secretion from cloned B cell lines, HIT-T15 and RINm5F. The effects of the islet cell hormones glucagon, somatostatin-28 and pancreatic polypeptide on insulin secretion from cultured cloned pancreatic B cells (H... D G,Lambert,T W,... - 《Journal of ...
Sirtuin 6 (Sirt6), a chromatin associated class III deacetylase, controls whole-body energy homeostasis and has a critical role in glucose-stimulated insulin secretion (GSIS) in pancreatic β cells. However, its underlying molecular mechanism remains poorly understood. To gain further insights, we ...
Several factors stimulate insulin secretion, but by far the most important is the concentration of glucose in the arterial (oxygenated) blood that perfuses the islets. When blood glucose concentrations increase (i.e., following a meal), large amounts of glucose are taken up and metabolized by ...