Insulin resistance is often associated with metabolic unhealthy obesity (MUO). Therapeutic approaches aiming to improve insulin sensitivity are believed to be central for the prevention and treatment of MUO. However, current antiobesity drugs are reported as multitargeted and their insulin-sensitizing ...
Insulin Resistance Treatment The goal of insulin resistance treatment is to lower your blood sugar levels and prevent type 2 diabetes. Medication for insulin resistance There's no medicine that can cure insulin resistance. But your doctor may prescribe drugs to treat other health issues you have, ...
These drugs have been linked to serious side effects like an increased risk ofheartfailure and bonefractures. Weight gain is another possible side effect. These medications are not usually given as a first-line treatment but may be helpful for some people. Alpha-glucosidase inhibitors Drugs of th...
These drugs also cause weight gain, averaging 5-10 pounds but considerably greater in perhaps one quarter of patients. When glycemic benefit is coupled with treatment of insulin resistance, both metformin and the thiazolidinediones are highly effective and reasonable agents and their use should be ...
E. Repurposing diabetes drugs for brain insulin resistance in Alzheimer disease. Diabetes 63, 2253–2261 (2014). Article PubMed PubMed Central Google Scholar Luchsinger, J. A. et al. Metformin in amnestic mild cognitive impairment: results of a pilot randomized placebo controlled clinical trial....
Dysregulation of free acid metabolism is a major contributor to the development of insulin resistance and diabetes. Mitochondrial trifunctional enzyme subunit (MTPα) has a critical role in fatty acid β-oxidation. However, the association between MTPα
In addition, insulin resistance seems to reduce the efficacy of cancer therapy. Treatment with cancer therapeutics such as glucocorticoids, chemotherapy, hormonal therapies and targeted drugs can actually induce insulin resistance. The question arises whether cancer-therapy induced insulin resistance impairs ...
Insulin resistance (IR) is a major metabolic risk factor even before the onset of hyperglycemia. Recently, berberine (BBR) is found to improve hyperglycemia and IR. In this study, we investigated whether BBR could improve IR independent of hyperglycemia. Acute insulin-resistant state was induced ...
exposure to beef insulin treatment are particularly prone to this resistance; clinically significant resistance usually occurs in patients with preexisting, significant tissue insensitivity to insulin; enhanced destruction of insulin at the subcutaneous injection site has also been implicated in resistance ...
Provided are a means for the prevention and treatment of obesity and/or insulin resistance and, particularly, pharmaceutical drugs for the treatment of obesity and/or insulin resist