Natural herbal remedies show promise in combating insulin resistance, with anthraquinone extracts garnering attention for their role in enhancing insulin sensitivity and treating diabetes. Anthraquinones are believed to ameliorate insulin resistance through diverse pathways, encompassing activation ...
On the contrary, the combination of HFD and low doses of STZ resulted in characteristic of T2DM; HFD induces insulin resistance and low doses of intraperitoneal STZ induce moderate impairment of insulin secretion [26–30]. In this study, OGTT, insulin secretion, and peripheral glucose ...
Mice in the HFD group were fed the HFD for 8 weeks to induce insulin resistance, whereas the normal diet group received the same volume of normal diet. HFD mice were then injected with STZ (100 mg/kg, intraperitoneally). The control group (CON), in parallel, was provided with a ...
and drug resistance would occur after long-termuse [8,9]. Therefore, a critical need exists for the discovery of alternative agents that would exert anti-hyperglycemic activity but exert fewer/no side effects. Traditional Chinese medicine and herbal remedies, which are multicomponent and have a lo...
Testicular dysfunction is a prevalent health problem frequently reported in individuals with diabetes mellitus (DM). Oxidative-inflammatory reactions, hormonal and spermatic abnormalities often accompany this illness. Herbal remedies "particularly wild plants" including chicory (Chicoriu...
One of the alternative herbal remedies used to treat Type 2 diabetes mellitus is Acalypha indica Linn (AI). The objective of this research is to investigate the effect of ethanol extract AI to insulin resistance. Thirty male Sprague-Dawley rats are divided into six group, four groups (negative...
Anti-insulin resistance bioactivityDXMS-induced insulin resistant HepG2 cellsMedicinal plants have a long history of use in China to treat diabetic symptoms.Ancient Chinese medical manuscripts and ethnobotanical surveys document plant remedies that continue to be actively used in China for the treatment...