Conclusions Hyperglycemia requiring insulin during induction chemotherapy in pediatric ALL is associated with an increased risk of short鈥恡erm and long鈥恡erm complications. Prospective studies are needed to analyze formal screening, preventive measures, and optimal management practices for hyperglycemia ...
fSevere hypoglycemia: an episode requiring assistance of another person to actively administer carbohydrate, glucagon, or other resuscitative actions.2 gBG-confirmed symptomatic hypoglycemia was defined as a BG measurement of <56 mg/dL with symptoms; nocturnal hypoglycemia was defined as an...
Insulin injection technique errors can cause a high rate of skin lipohypertrophic lesions (LHs), but these lesions are often flat and barely visible, thus requiring thorough deep palpation examination and ultrasonography (US) for identification. Detection of LHs is crucial to prevent poor diabetes co...
thus being a prerequisite for the energy-requiring process of gluconcogcnesis (6). Furthermore. glycerol is rapidly converted to glucose in the liver (I). In our patient the concen- trations of free fatty acids and ketone bodies were in the lower normal range before glucagon treatment. and...
in patients with insulin-requiring type 2 diabetes need to be identified. Methods: A retrospective, multi-center, observational study was conducted for outpatients with oral antidiabetic drug (OAD)-treated type 2 diabetes whose A1C levels remained above 7%. Patients were begun on basal insulin ...
9.3%in the insulin glargine U-100 group aMACE=cardiovascular death, nonfatal MI, or nonfatal stroke. bSevere hypoglycemia was defined as an episode requiring assistance of another person to actively administer carbohydrate, glucagon, or other resuscitative actions and dur...
cSevere hypoglycemia was defined as an episode requiring assistance of another person to actively administer carbohydrate, glucagon, or other resuscitative actions and during which plasma glucose concentration may not have been available, but where neurological recovery following the return of ...
The UPR response is triggered by the activation of three main sensors of ER stress: inositol requiring kinase 1 (IRE1), activating transcription factor 6 (ATF6) and protein kinase-like ER kinase (PERK). IRE1 phosphorylates JNK, which in turn leads to impaired insulin signalling by inhibiting...