Lynch PM,Riedel AA,Samant N,et al.Resource utilization withinsulin pump therapy for type 2 diabetes mellitus[].Am J ManagCare.2010Lynch P M,Riedel A A,Samant N, et al.Resource utilization with insulin pump therapy for type 2 diabetes mellitus.. American Journal of Managed Care . 2010...
Emerging evidence for the use of insulin pump therapy in infants, toddlers, and preschool-aged children with type 1 diabetes. Pediatr Diabetes 2006;7 Suppl 4:15-9. 16. Tubiana-Rufi N. Insulin pump therapy in neonatal diabetes. Endocr Dev 2007;12:67-74. www.e-apem.org...
The year 2021 marks the centennial of Banting and Best’s landmark description of the discovery of insulin. This discovery and insulin’s rapid clinical deployment effectively transformed type 1 diabetes from a fatal diagnosis into a medically manageable
A continuous insulin infusion (via insulin pump ) with meal-time boluses is also an option. Type 2 diabetes mellitus: Added when oral therapy has failed to provide adequate glucose control Usually used in addition to other oral antidiabetic medications (e.g., metformin ) Indicated for initial...
Results from western blotting and immunohistochemistry indicated that PGE1 remarkably restored autophagy, insulin resistance and the FGF21 expression in rat kidney of type 2 diabetes mellitus (T2DM). Collectively, we demonstrated the potential protection of PGE1 on insulin resistance in renal tubules via...
Insulin pump vs. syringe use for Bolus Insulin In the Basal Insulin section pumps were mentioned as having a particular utility, inasmuch as they can be programmed for the different rates needed during the day, especially during the dawn phenomenon period. Bolus insulin, however, is usually admin...
For intra-ARC infusions, mice were implanted with a bilateral cannula (Plastics One) 1.4 mm caudal of bregma, extending 5.7 mm below dura, connected to a minipump (Alzet model 1002, DURECT Corp) via PEG tubing and a Y connector. Mice received 6 day infusions of vehicle, leptin (4.8 μ...
The spontaneously hypertensive/NIH-corpulent (SHR/N-cp) rat is a genetic model that exhibits both non-insulin-dependent diabetes mellitus (NIDDM) and hypertension. To determine the impact of long-term treatment with the long-acting angiotensin-converting enzyme (ACE) inhibitor perindopril (PE) on ...
Reduced insulin sensitivity (insulin resistance) is a hallmark of normal physiology in late pregnancy and also underlies gestational diabetes mellitus (GDM). We conducted transcriptomic profiling of 434 human placentas and identified a positive associati
Pharmacological inhibition of epoxide hydrolase or deletion of the gene encoding soluble epoxide hydrolase (Ephx2) preserves islet cells in rodent models of type1 diabetes and enhances insulin sensitivity in models of type2 diabetes, as does administration of epoxyeicosatrienoic acids or their stable ...