In this context, the present review aims to highlight that prospection of insulin-like proteins in plants is of the utmost importance both for finding new drugs for the treatment of diabetes and for shedding light on the mechanisms involved in diabetes. (C) 2016 Elsevier B. V. All rights ...
Daniell has led the charge on medicine made of plant-grown proteins for at least 8 years. In 2015, the Penn investigator published a paper that argues low-cost drugs developed from lettuce plants are commercially viable. In that study, he looked at plant-based medicin...
The risk of inducing hypoglycaemia (low blood glucose) constitutes the main challenge associated with insulin therapy for diabetes1,2. Insulin doses must be adjusted to ensure that blood glucose values are within the normal range, but matching insulin do
Plants from the genus Eugenia as promising therapeutic agents for the management of diabetes mellitus: A review Nayara MacêdoPeixoto Araujo, ...Glaucia MariaPastore, inFood Research International, 2021 5.2.4Increased insulin secretion Insulin is a hormone synthesized by pancreatic β-cells to regulate...
Viscum album (mistletoe) has been documented as a traditional treatment of diabetes. In acute 20-min tests, 1-10 mg/ml aqueous extract of mistletoe evoked a stepwise 1.1- to 12.2-fold stimulation of insulin secretion from clonal pancreatic B-cells. This effect was abolished by 0.5 mM diazoxid...
α-glucosidase inhibitors from plants: A natural approach to treat diabetes. Diabetes is a common metabolic disease characterized by abnormally high plasma glucose levels, leading to major complications, such as diabetic neuropathy,... Kumar,Sunil,Narwal,... - 《Pharmacognosy Reviews》 被引量: 284...
Fluocinolone acetonide intravitreal implant for the treatment of diabetic macular edema 热度: efficacy of composite extract from leaves and fruits of medicinal plants used in traditional diabetic therapy against oxidative stress in alloxan-induced diabetic rats ...
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A fusion protein derived from plants holds promising potential as a new oral therapy for type 2 diabetes We demonstrated that plant-made Ex-4-Tf retained the activity of both proteins. In particular, the fusion protein stimulated insulin release from pancreatic... C Jeehye,D Hong,F Zhi-Chao...
In the search for novel PPARγagonists, we screened a library of natural products and identified podophyl- lotoxin (Fig. 1), which is extracted from plants of the genus Podophyllum, and found that it exhibits partial acti- vation of PPARγand the capacity to reverse insulin ...