Methods: Eligible patients were those using regular insulin before main meals and a basal neutral protamine Hagedorn (NPH) insulin. Study group patients were those who chose to convert to lispro insulin. Patients who elected not to change their regimen were used as a comparison group. Follow up...
intermedia;long-acting —insulina de acción prolongada;NPH —insulina NPH;pre-mixed —insulina premezclada;rapid-acting —insulina de acción rápida;rapid-acting — analogueanálogo de insulina de acción rápida;recombinant —insulina recombinante;regular —insulina regular;to take —inyectarse ...
The first human insulin analogue was insulin lispro (Eli Lilly), which was designed to replicate the sequence of lysine and proline at B28, B29 in insulin-like growth factor 1 (IGF-1) which does not self-associate. The low propensity of lispro to self-associate leads to a rapid dissocia...
long-acting — insulina de acción prolongada; NPH — insulina NPH; pre-mixed — insulina premezclada; rapid-acting — insulina de acción rápida; rapid-acting — analogue análogo de insulina de acción rápida; recombinant — insulina recombinante; regular — insulina regular; to take —...
Randomized Cross-Over Trial of Insulin Glargine Plus Lispro NPH Insulin Regular Human Insulin in Adolescents With Type 1 Diabetes on Intensive Insulin Regi... OBJECTIVE -- To compare blood glucose control and incidence of nocturnal hypoglycemia in adolescents with type 1 diabetes on multiple injection...
Hordern SV, et al. Comparison of the effects on glucose and lipid metabolism of equipotent doses of insulin detemir and NPH insulin with a 16-h euglycaemic clamp. Diabetologia. 2005;48(3):420–6. ArticleCASPubMedGoogle Scholar Edgerton DS, et al. Targeting insulin to the liver corrects ...
Lispro Aspart Glulisine Short acting: Still absorbed rapidly Slightly longer peak effect Example: regular Intermediate acting: Absorbed more slowly Lasts longer Example: neutral protamine Hagedorn ( NPH ) Long acting: Absorbed slowly Minimal peak effect (provides a stable plateau effect) Lasts most...
NPH human insulin (human insulin isophane suspension) Humulin N Novolin N Long acting • Starts working within 2 to 4 h • Lasts in the body for up to 24 h Insulin glargine Lantus Toujeo Insulin detemir Levemir Insulin analog Tresiba Intermediate and rapid acting 75% insulin lispro protamin...
Lispro 10–15 min 1–2 h 3–5 h Insulin pump, mealtime and high blood sugar correction Insulin pump, mealtime and high blood sugar correction Short-acting insulin Regular 30 min 2–3h 6.5 h Not typically used outpatient Used in IV drips of insulin Intermediate-acting insulin NPH 1–3 h ...
Efficacy of Conversion From Bedtime NPH Insulin Injection to Once- or Twice-Daily Injections of Insulin Glargine in Type 1 Diabetic Patients Using Basal/Bo... Diabetes Care. 2004 Feb;27(2):632-3. Clinical Trial; Comparative Study; Controlled Clinical Trial; Letter E Albright - 《Diabetes Care...