Insulin detemir is another long-acting analogue created by the addition of a fatty acid moiety to position 29 of the beta chain. This fatty acid binds albumin in circulation and slows activity. There is limited experience with this analogue in dogs and cats and no dose has been established fo...
The market offers insulin lispro, aspart, and glulisine in this category, all of which have been modified to adjust the amino acid sequence of the B chain in order to decrease the formation of zinc mediated hexamers, a feature present in regular insulin. The human insulin segment is expected...