Insulin signaling is necessary for vitellogenesis in Drosophila melanogaster independent of the roles of juvenile hormone and ecdysteroids :female sterility of the chico insulin signaling mutation is autonomous to the ovary[J]. Journal of Insect Physiology, 2005, 51(4):455-464. [43]Wigby S, ...
Insulin, a 7,000 Da protein, known as “the most potent anabolic hormone”, is produced and secreted by the pancreatic ß-cells and exerts metabolic and mitogenic effects in several target tissues.1,2The presence of insulin in the cerebrospinal liquid has been recognized for many years and ...
Insulin resistance is not a disease as such but rather a state or condition in which a person's body tissues have a lowered level of response to insulin, a hormone secreted by the pancreas that helps to regulate the level of glucose (sugar) in the body. As a result, the person's body...
Regulation of cuticle pigmentation in Drosophila by the nutrient sensing insulin and TOR signaling pathways[J]. Developmental Dynamics, 2013, 243(3):393-401. [31] Nakahara Y, Matsumoto H, Kanamori Y, et al. Insulin signaling is involved in hematopoietic regulation in an insect hematopoietic ...
Insulin is able to reverse all these phenomena by favoring storage and swift intake of glucose into the tissues, by decreasing the breakdown of stored fat, and by promoting protein synthesis. When insulin is secreted or given in excess, it may lower the blood sugar level much below its ...
A form of bioregulation in which a secreted factor affects only the cell from which it was secreted. GROWTH HORMONE A polypeptide that is produced by the anterior pituitary gland that, among other functions, stimulates the liver to produce IGF1. ENDOCRINE A form of signalling whereby hormones ...
MIF is released in vivo from activated immune cells as well as by the anterior pituitary gland upon stimulation of the hypothalamic-pituitary-adrenal axis. MIF also has been found to be secreted together with insulin from the pancreatic 尾-cells and to act as an autocrine factor to stimulate ...
adult is marked by the rising influence of the pituitary gland in Other organs showed moderate pituitary dependence in the maintenance of normal somatic growth ( 1 -5). GH. the major proportion to body weight. Serum IGF-I and IGF-I1 were promoter of body weight gain and IGF-I and -11...
In addition, in these animals, the splenic extremity of the gland is not too deeply located and can be removed without much difficulty. Paulescu demonstrated the requisite of complete ablation to induce experimental diabetes...
Its determi- nation in blood and urine is carried out by the procedure indicated above (T.I., p. 99). The separation of urea from blood is done in the same way as for glycose. Its determination is carried out with the help of sodium hypobromite. Paulescu transferred the fresh gland ...