Insulin derivatives are bonded to the branched polymer is well defined structurallyInsulin conjugated with structurally well defined, bifurcated and trifurcated polymers can be use by pulmonary delivery for systemic absorption through the lungs to reduce or eliminate the need for administering other ...
Glucose-responsive insulin delivery systems that mimic pancreatic endocrine function could enhance health and improve quality of life for people with type 1 and type 2 diabetes with reduced β-cell function. However, insulin delivery systems with rapid i
5f). This resulted from the fact that the deprotonation of chitosan happened at higher pH, which caused a less compact polymer network and the release of the loaded insulin. Furthermore, the insulin NPs spray-dried with no mannitol showed a faster release profile than other dehydrated NPs (...
Cat No.KHC0004 库存:现货 Size Choose Control Slide 点击咨询在线客服 Counter Staining Reagent5 mLRTU Mounting Media5 mLRTU Datasheet1 Copy Manual1 Copy Background Information Insulin(INS) is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and...
The polymer coating dissolves when it reaches a more alkaline environment in the small intestine, where the ionic liquid carrying insulin is released. When a protein molecule such as insulin enters the intestine, there are many enzymes whose function is to degrade the proteins into smaller amino ...
(the “Cori ester”) and a glycogen primer, catalyzed the synthesis of glycogen or, to be more precise, of an amylose-like, linear glucose polymer (branching had not yet been discovered) that gave a blue color with iodine instead of the normal mahogany tinge (the so-called “blue” ...
of a polymer that slowly dissolves after injection5; b) compounds with a peptide structure similar to mammalian GLP-1 (dulaglutide and albiglutide) were coupled with large proteins (immunoglobulin Fc fragments and albumin, respectively)6,7; c) a liraglutide-like GLP-1 analogue,semaglutide, was ...
High hepatitis C viral load is associated with insulin resistance in patients with chronic hepatitis C A synthetic sulphited polymer based on a urea - paraformaldehyde condensate has been prepared to be used as pre and retanning agent. The influence of the p... Ching-Sheng,Hsu,Chun-Jen,......
In the case of type 1 diabetes, the best known therapeutic method is for the patient to check the blood sugar level with a biosensor and inject insulin or other hypoglycemic agent, although it is not a complete remedy. However, administration of the drug by injection may drastically lower ...
#2008 The Society of Polymer Science, Japan SHORT COMMUNICATION Preparation of Layer-by-layer Thin Films Containing Insulin and its pH-Sensitive Decomposition By Kentaro YOSHIDA, Hiroshi SATO, Shigehiro TAKAHASHI, and Jun-ichi ANZAIÃ KEY WORDS: Insulin / Controlled Release / Layer-by-layer / ...