BACKGROUND: Although it is well known that insulin secretory defects and insulin resistance are major pathogenetic factors of type 2 diabetes, their relative importance still remains controversial in various ethnic groups. Increased leve... EK Byun,YS Hong,JY Oh,... 被引量: 0发表: 2003年 Gluco...
In cardiology is well-known a ... T Svaina - 《Vnitrní Lékarství》 被引量: 2发表: 2014年 Sex differences in the association of endogenous sex hormone levels and glucose tolerance status in older men and women Some evidence suggests an inverse association between type 2 diabetes and ...
The beneficial effect of physical activity in the general population is well known, but, to the authors' knowledge, has not been reported for persons with ... Moy Claudia S,TJ Songer,LaPorte Ronald E,... - 《American Journal of Epidemiology》 被引量: 559发表: 1993年 Endothelial dysfunction...
Havelock JC, Bay K, Ivell R, Bathgate RA, Rodgers RJ, Carr BR. A novel hormone known as insulin-like factor 3 (INSL3) is expressed in the human ovary and serum levels are increased in women with polycystic ovary syndrome (PCOS). Fertil Steril 2005; 84(Suppl. 1):S3....
(IGFBP1) as the most strongly associated placental transcript. IGFBP1 is a binding protein that is produced primarily by the liver outside of pregnancy and is highly expressed by the placenta16. IGFBP1 has been implicated in the modulation of the biological activity of insulin-like growth ...
We further examined the GPR43-mediated intracellular signalling in 3T3-L1 pre-adipocyte-derived adipocytes. Phenylacetamide (PA) is known as a GPR43-selective agonist31, while cyclopropanecarboxylic acid is a partially selective GPR41 agonist (Supplementary Fig. S4a,b). Acetate and PA significantly ...
Imaging tests.You may also get an imaging test such as a CT scan, ultrasound, orMRIso your doctor can see where the tumor is. Insulinoma Treatments The main treatment for an insulinoma is surgery to remove the tumor. Most of the time, that will cure you. ...
we did not observe the α-CT motif in our structure of the IR/S597 complex, which suggests that once the α-CT is released from the L1 domain, it becomes disordered. Subsequently, the two protomers would undergo rigid-body rotation using the L2-FnIII-1 interface as the hinge. Finally,...
Thereby, produced insulin NPs are often found unsuitable for creating dry powdered formulations such as oral tablets and oral films since vast amounts of dry nanoparticles are required to achieve the therapeutic window of the insulin. Spray drying is a well-known and inexpensive industrial-scale ...
These excess nutrients are stored as triglycerides, commonly known as fat, and the adipocytes where triglycerides are stored, are known as fat cells. The primary composition of the adipose tissue is adipocytes. Adipose tissue is a large and dynamic endocrine organ responsible for energy storage, ...