But due to several complications like continuous infusion of insulin, frequent blood glucose infusion and overall withdrawals of blood samples at different time intervals, it is difficult to apply in large-scale screening purposes3,4. Therefore, the different surrogate techniques such as the ...
In health glucose-dependent insulinotropic polypeptide (GIP) is a potent glucose-lowering peptide that does not cause hypoglycaemia. The objectives of this study were to determine the effects of exogenous GIP infusion on blood glucose concentrations, glucose absorption, insulinaemia and gastric emptying...
In the pregnancy studies presented here, a two-hour hyperglycaemic clamp at two time points in the later half of gestation, reduced NEFA concentrations by approximately 50%, but maternal insulin release in response to glucose remained suppressed. This is in contrast to the same protocol in NPNL...
Male Sprague–Dawley rats were randomized to laparotomy (Sham) or to cecal ligation and puncture (CLP), with postoperative saline infusion (Starve), with EN or with PN for 72 hours. Serum levels of IL-6 and IL-10 were measured by immunoassay, and hepatic expressions of cytokine-inducible ...
The main delivery parameters (flow rate, dose, applied force on the MNA, MNA size, anatomical delivery site) were analyzed in order to explain the limitation of the process and the transfer efficiency (rate-limiting factors). As a result, we established a delivery protocol that assured a ...