Shmueli E,Record CO,Alberti KG,et al.Insulin independent glucose uptake in cirrhosis.Hepatology. 1995Shmueli E,Record CO,Alberti KG,et al.Insulin independent glucose uptake in cirrhosis. Hepatology . 1995Shmueli E,Record CO,Alberti KG,et al.Insulin independent glucose uptake in cirrhosis. ...
a得到客户订单 Obtains the customer order form[translate] a一般按默认,一直点“下一步”即可 Presses the default generally, selects continuously “next step” then[translate] ainsulin-stimulated glucose uptake 胰岛素被刺激的葡萄糖举起[translate]
The present study asks if this is a direct effect of increased glucose uptake by skeletal muscle. Incubation of primary human skeletal muscle cells (HSKMCs) with apoA-I increased insulin-dependent and insulin–independent glucose uptake in a time- and concentration-dependent manner. The increased ...
Because glucose uptake and MHC expression were both determined at the whole muscle and single fiber levels, it is possible to compare the magnitude of the directly measured HFD-induced insulin resistance for whole muscle with an estimate of the magnitude of whole muscle insulin resistance that relie...
These results indicate that a substantial age-related decrement in 2-DG uptake occurs in several limb muscles from rats at 21 vs. 28-35 days by a mechanism that is independent of GLUT-4 levels and not specific for the insulin-dependent pathway. 展开 ...
significantlyincreasedglucoseuptakeataconcentra- tionof500ng/mL.Inaddition,theproteinsynthesis inhibitorcycloheximide(0.5mg/mL)counteractedthe insulin-elevatedglucoseuptake,therebysuggestingthat newlysynthesizedtransporterproteinmighttakepart intheinsulin-inducedglucoseuptake.Furthermore, pretreatmentofthecellswithSB203580...
Hexosamines have a negative feedback effect on GLUT4, and reduced GLUT4 activity decreases insulin-mediated glucose uptake. Thus, insulin-independent glucose transport through GLUT1 can meet the basal needs of the muscle cell. If glucose entrance through GLUT1 and the activation of the hexos...
To assess individual factors responsible of overall glucose tolerance after successful pancreas transplantation, an i.v. glucose tolerance test, with frequent blood sampling and tolbutamide administration to elicit a second insulin response was used to estimate insulin sensitivity (SI) and glucose effective...
Even at high insulin concentrations, free glucose was not detected in the muscle cells of young or old rats, the uptake of 2-deoxyglucose diminished in parallel with that of glucose, and there was no evidence of a defect in glucose metabolism. These findings indicate that in the Sprague-...
n = 3 independent replicates. For some datapoints, the s.d. error bars are shorter than the size of the symbols. e, Representative curves of NNC2215 and insulin degludec dose-dependent conversion of 3H-d-glucose into lipid in isolated rat adipocytes at low (3 mM) and high (20...