Background:It is thought that a reduction in the frequency of basal insulin injections might facilitate treatment acceptance and adherence among patients with type 2 diabetes.Insulin icodec is a basal insulin analogue designed for once-weekly administration that is in development for the treatment of ...
Clinical trials have shown that insulin analogues, such as glargine, detemir, aspart, and lispro, do not offer major advantages over human insulin products, such as neutral protamine Hagedorn (NPH) and regular human insulin, for patients with type 2 diabetes.1,2 In these studies, nei...
currently is being reviewed by the FDA. In this industry-sponsored multicenter trial, 145 patients whose type 2 diabetes was not controlled adequately by diet and exercise alone were randomized to receive either inhaled insulin (given before each meal, with dose adjustments as needed) or rosiglitazo...
et al. Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes. Arch. Neurol. 68, 51–57 (2011). Article PubMed Google Scholar Willette, A. A. et al. Association of insulin resistance with...
Visual Abstract. Once-Weekly Insulin Icodec vs Once-Daily Insulin Degludec in Adults with Insulin-Naive Type 2 Diabetes View LargeDownload Figure 1. Flow of Participants in a Trial of Once-Weekly Insulin Icodec vs Once-Daily Insulin Degludec for Type 2 Diabetes...
Scherbaum WA: Do patients with type 2 diabetes on peritoneal dialysis need less insulin if they are given rosiglitazone? Nat Clin Pract Nephrol 2006, 2: 312–313.Scherbaum WA: Do patients with type 2 diabetes on perito- neal dialysis need less insulin if they are given rosiglitazone? Nat ...
Many forms of insulin treat diabetes. They're grouped by how fast they start to work and how long their effects last. Thetypes of insulininclude: Rapid-acting:This type of insulin starts to work in about 15 minutes and lasts for 1 to 5 hours, depending on which type you use. You take...
March 29, 2012 (New Orleans, Louisiana) — Insulin administration has traditionally been one of the last steps in the treatment of type 2 diabetes mellitus (T2DM), but that's changing, says Jonathan Marquess, PharmD, from the Institute for Wellness and Education Inc in Atlanta, Georgia. He...
To prevent hyperinsulinemia, which may cause atherosclerosis, thiazolidinediones (TZDs), also known as insulin sensitizers, are often added to the therapeutic regimen of patients with type 2 diabetes who are receiving insulin. The combination of insulin with pioglitazone, a TZD, reduces glycoated hemog...
Insulin is a hormone that helps the body regulate sugar in the blood and is a key component of treatment for many patients with type 2 diabetes. Older adults who continue to use insulin are at greater risk of dangerouslylow blood sugar, or hypoglycemia; this can happen when people take too...