Flow chart of study population divided by sex, presence of first non-fatal myocardial infarction, and glycaemic states defined according to OGTT. IFG = impaired fasting glucose; IGT = impaired glucose tolerance; NGT = normal glucose tolerance; OGTT = oral glucose tolerance test;...
473,444 excluded individuals met the specific criteria: (1) Missing baseline results of sex, height, fasting plasma glucose (FPG), and weight. (2) Extremely low BMI (< 15 kg/m²) and high BMI (> 55 kg/m²). (3) Less than 2 years between visits. (4) Baseline diagnosis ...
FPG = fasting plasma glucose; γGT = gamma glutamyltransferase; GS = glycogen synthase; HDL = high density lipoprotein; HSC = hepatic stellate cells; hSkMc = human skeletal muscle cells; IFG = impaired fasting glucose; IGT = impaired glucose tolerant; IL-6...
Fasting hyperglycemia in type 2 diabetes mellitus (T2DM) results from elevated endogenous glucose production (EGP), which is mostly due to augmented hepati... E Phielix,J Szendroedi,M Roden - 《Trends in Pharmacological Sciences》 被引量: 104发表: 2011年 Novel Insulin Sensitizer Modulates Nutrie...
4 show the results of the ROC curves. The TyG-BMI demonstrated superior predictive ability for insulin resistance (defined as HOMA-IR ≥ 2.2) with an AUC of 0.81, compared to the TyG’s AUC of 0.77 (P < 0.001). As for the live birth in fresh ET cycles, the AUCs of TyG-...
known as sodium-glucose co-transporter 1 and 2 inhibitors (SGLT1/2 inhibitors). It is being studied for use in both type 1 diabetes and type 2 diabetes management. Clinical trials and research on Sotagliflozin have shown promising results, particularly in its potential effectiveness when used ...
Results A total of 6,271 patients with AIS were included in this study. The median values of eGDR in lower and higher eGDR group were 5.0 mg/kg/min (interquartile range, 4.2–5.6) and 7.6 mg/kg/min (interquartile range, 6.8–9.6), respectively. Patients with higher eGDR were signifi...
Fasting blood levels of liver enzymes (ALT, AST), insulin, glucose, lipid profile (Cholesterol, TG, HDL, LDL), adiponectin, leptin, IL-6, and TNF-a were obtained in all children. Obesity was define according to the CDC BMI chart (BMI > 95%) and IR was calculated according to the ...
TITRATE dose up or down in increments of 2 to 4 units/week based on metabolic needs, blood glucose monitoring results, and glycemic goal until desired fasting plasma glucose is achievedMaintenance dose: 15 to 60 units per day Maximum dose: Insulin glargine 60 units/lixisenatide 20 mcg once a...
Results The intra-operative target CBG range was achieved in both groups, with no statistically significant difference between them. However, in the post anesthesia care unit (PACU), the number of patients who achieved the target CBG range was significantly more in the BII group. The decrease in...