The long-acting insulin analogues are clear, as are the soluble insulins. Therefore, it is very important when teaching people about their insulin to develop a way to differentiate the bottles. NPH and soluble insulin can be mixed without changing either of the insulins. In some countries it...
partial agonist that has less than 80% (or 70%) activity at the insulin receptor as does native insulin. These insulin analogues, which have reduced activity at the insulin growth hormone receptor and enhanced activity at the insulin receptor, include both heterodimers and single-chain analogues....
6777207 Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast 2004-08-17 Kjeldsen et al. 6551992 Stable insulin formulations 2003-04-22 DeFelippis et al. 6521738 Method for making insulin precursors and insulin precursor analogs 2003-02-18 ...
Dual agonist compounds polipptido insulinotrpico glucose dependent Peptide product (GIP) - similar to GLUCAGN \\/ 1 (glp-1) and MethodsThis refers to acilados GIP analogues that have a dual activity with respect to GIP and glp-1 and its use in the treatment of Metabolic Disorders, such ...
In the context of insulin, inactivation of regulators 4E-BP1 and 4E-BP2 causes insulin resistance8, and treatment with rapamycin and its analogues (rapalogues) generates glucose intolerance9 or even the onset of insulin resistance10. These data leave unresolved the issue on the druggability of ...
insulin administration and postprandial glucose due to unforeseeable trends in glucose absorption following meals characterized by post-prandial hyperglycemic excursions and tardive post-prandial hypoglycemia due to the delay in the insulin action of currently available rapid-acting insulin analogues [58]. Cu...
The introduction of FDA-approved pharmaceutical grade IGF-1 products in the form of Increlex and Iplex is likely to have seen an increase in rhIGF-1 abuse by athletes [97] and in the years that followed a number of newer IGF-1 compounds, analogues and products also became available, some...
International Journal of Molecular Sciences Article Multifunctional Composite Microcapsules for Oral Delivery of Insulin Shaoping Sun 1, Na Liang 2,*, Xianfeng Gong 1, Weiwei An 3, Yoshiaki Kawashima 4, Fude Cui 5 and Pengfei Yan 1,* 1 Key Laboratory of Chemical Engineering Process and Technology...
4-Hydroxyisoleucine: Effects of synthetic and natural analogues on insulin secretion. Eur. J. Pharmacol. 2000, 390, 339–345. [CrossRef] 84. Yadav, U.C.S.; Moorthy, K.; Baquer, N.Z. Effects of sodium orthovanadate and Trigonella foenum-graecum seeds on hepatic and renal lipogenic ...
Several GLP-1 analogues, more stable and more slowly degraded than GLP-1 native, have been developed; among these, exenatide, liraglutide and lixisenatide cross the BBB and, independently from their effects on glucose control, influence cellular pathways of neuronal protection, mitochondrial function,...