In 1923, the first insulin commercially available was in concentrations of 3–5 units/mL. With the advent of continual process improvements, concentrations of insulin formulations increased rapidly to 20 units/mL administered using a syringe designed with 20 division marks per mL, then to be follow...
Abstract #234: Regular Insulin Administered with the V-Go Disposable Insulin Delivery Device in a Clinical Diabetes Setting: A Retrospective Analysis of Efficacy and Costdoi:10.1016/S1530-891X(20)44942-0David SuttonCharissa HigdonMark Carmon
say, the jet injectors are a solution for patients with needle phobia [127]. Recent safety and feasibility studies have evaluated the treatment efficiency and pharmacokinetic and pharmacodynamic (PK-PD) profiles of the insulin administered by the new-generation jet injectors [127,128]....
insulin aspart was administered before mating, during mating, and throughout pregnancy. Further, in a pre- and postnatal development study insulin aspart was given
Insulin can be administered via: ■ syringe; ■ insulin pen; ■ insulin pump; ■ jet injector. The current mode of administration of insulin is via subcutaneous injection by means of syringes. A summary of advantages and disadvantages of insulin delivery devices is given in Table 1.4. Table 1....
When administered intravenously, another insulin lispro product, 100 units/mL demonstrated dose-dependent clearance, with a mean clearance of 21.0 mL/min/kg (0.1 unit/kg dose), and 9.6 mL/min/kg (0.2 unit/kg dose). Another insulin lispro product, 100 units/mL, demonstrated a mean t1/2 of...
These advanced insulin pens have the capability to log details of insulin doses, such as the timing and quantity of insulin administered. The collected data can then be synchronized with a compatible application, allowing both individuals with diabetes and their healthcare providers to review the ...
Insulin is usually administered by injection under the skin (subcutaneously). The subcutaneous tissue of the abdomen is preferred because absorption of the insulin is more consistent from this location than subcutaneous tissues in other locations. When insulin was first discovered and made available for...
On days 1–7 participants took variable doses of prandial insulin (insulin glulisine, administered in disposable pens for SC injection) at mealtimes as needed, in addition to the fixed daily basal insulin doses. The basal insulin dose on day 8 of each treatment period was given in fasting ...
Insulin pumps are wearable medical devices that inject rapid-acting insulin in the subcutaneous tissue of the abdomen at almost continuous time, by a cannula connected to a disposable reservoir of insulin in the pump. A small basal dose is administered throughout the day to keep blood glucose (...