In practice, the insertion point of the implant is located in the lateral cortical area of the proximal femur. Unnecessary iatrogenic injury can be effectively avoided only by establishing an SZ at the beginning of needle insertion. As shown in the axial view in Fig.8C, the “narrow FN” c...
Background Choroideremia is an X-linked retinal disease characterized by progressive atrophy of the choroid and retinal pigment epithelium caused by mutations in the CHM gene. SVA (SINE-R/VNTR/Alu) elements are a type of non-autonomous retrotransposon that occasionally self-replicate, reinsert ...
Studies with ClC-5 knockout mice showed that loss of ClC-5 function results in an endosomal acidification defect and reduced proximal tubular protein reab- sorption, which explain the symptoms of Dent's disease (Piwon et al. 2000). Based on the results obtained with the Alu insertion ...
constitute the short arms of five acrocentric chromosomes18, cell function is not compromised by retroelement-insertion-mediated inactivation of a few, or in some organisms at least half, of the rDNA units19,20. Although rDNA arrays are prone to restructuring in meiosis, cancers or cells with sp...
Reuse of the recovered ligand in a model reaction under standard conditions afforded product 3a an 86% yield and 95:5 er, indicating that the ligand could be largely recycled and reused without loss of catalytic activity and enantioselectivity (Figure 3b). In order to understand the mechanistic ...
The IS6 family of bacterial and archaeal insertion sequences, first identified in the early 1980s, has proved to be instrumental in the rearrangement and spread of multiple antibiotic resistance. Two IS, IS26 (found in many enterobacterial clinical isola
We repeated this experiment and investigated whether there was any loss in EGFP-calneuron-1 fluorescence after digitonin permeabilization in different cellular compartments. To obtain a readout for permeabilization efficiency, COS-7 cells were co-transfected with a construct expressing soluble red ...
Such abnormal expression is usually considered pathological because it can contribute to calcium-dependent cell loss after seizures and the development of acquired epilepsy. Some studies even propose the CP-AMPARs as a therapeutic target [3,23,71,72]. Our previous study demonstrated that CP-AMPARs...
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Keywords: noise barrier; insertion loss; vehicle frequencies; diffraction; flow speed 1. Introduction The rapidly increasing number of vehicles is in the world, especially in many developing countries, has raised the serious problem of traffic noise [1–3]. Traffic noise is disturbing to the ...