K. Molecular mechanism of inositol hexaphosphate-mediated apoptosis in human malignant glioblastoma T98G cells. Neurochem. Res. 32, 2094–2102 (2007). Article CAS PubMed Google Scholar Vucenik, I. et al. Anti-angiogenic activity of inositol hexaphosphate (IP6). Carcinogenesis 25, 2115–2123 (...
In all cells, inositol-1-phosphate is synthesized from glucose-6-phosphate. In plants there are significant amounts of inositol phosphate, including hexaphosphate orphytic acid, achelatorof calcium, iron, magnesium and zinc; it forms insoluble products that cannot be absorbed. It is widely dist...
The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein J. Biol. Chem., 274 (31) (1999), pp. 21735-21740 View PDFView articl...
The crystal structure of the HDAC1:MTA1 complex bound to a novel peptide-based inhibitor and to inositol hexaphosphate suggests a molecular basis of substrate recognition, and an entropically driven allosteric mechanism of activation. 1 Henry Wellcome Laboratories of Structural Biology, Department of ...
Inositol hexaphosphate (IP 6 - ), a type of phytic acid and its salt (e.g. sodium phytate) have been reported to have anti corrosion properties on copper surfaces [27,28]. Sodium based phytic salts which are completely soluble in water form self-assembled mono- layers (SAMs) on the cop...
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Abstract Myo-inositol hexakisphosphate (IP6) is a natural product known to inhibit vascular calcification (VC), but with limited potency and low plasma exposure following bolus administration. Here we report the design of a series of inositol phosphate analogs as crystallization inhibitors, among which...
A 1.2 gram quantity of the sodium salt of epi-inositolhexaphosphate produced according to Example 28 was dissolved in 500 ml sodium acetate buffer, pH 5.2 2.0 gram wheat phytase (EC 3.1.3.26, 0.015 U/mg from Sigma Chemical Co.) was incubated at 38° C. After the liberation of 50% ino...
46, pp. 81-92 (1980); Gersonde, et al., “Enhancement of the O2 Release Capacity and of the Bohr-Effect of Human Red Blood Cells after Incorporation of Inositol Hexaphosphate by Fusion with Effector-Containing Lipid Vesicles”, Origins of Cooperative Binding of Hemoglobin (1982); and Weiner...
“Enhancement of the O2Release Capacity and of the Bohr-Effect of Human Red Blood Cells after Incorporation of Inositol Hexaphosphate by Fusion with Effector-Containing Lipid Vesicles”, Origins of Cooperative Binding of Hemoglobin, (1982); and Weiner, “Right Shifting of Hb-O2Dissociation in ...