iNOS/COX-2 pathway interaction: a good molecular target for cancer treatment . Current Enzyme Inhibition . 2005; 1 ( 2 ): 97–105.Cianchi F, Perna F, Masini E. 2005. iNOS/COX-2 pathway interaction: a good molecular target for cancer treatment. Current Enzyme Inhibition 1: 97-105....
Crocin II 是一种NO抑制剂,抑制NO产生,也是 iNOS抑制剂,COX-2抑制剂。 产品性质 英文别名(English Synonym) Crocin II 中文名称(Chinese Name) / 靶点(Target) Others 通路(Pathway) Immunology/Inflammation CAS号(CAS NO.) 55750-84-0 分子式(Formula) ...
Ginsenoside C-K 是一种一氧化氮合酶抑制剂(iNOS抑制剂)和 COX-2抑制剂 。 产品性质 英文别名(English Synonym) Ginsenoside C-K 中文名称(Chinese Name) 人参皂苷 C-K 靶点(Target) cell cycle arrest CYP2C9 CYP2A6 通路(Pathway) Immunology/Inflammation ...
We concluded that COX-2 mediates morphine-induced delayed cardioprotection via an iNOS-dependent pathway. (c) 2005 Elsevier Inc. All rights reserved.Jiang XJShi EYNakajima YSato SLife sciencesJiang X, Shi E, Nakajima Y, et al. COX-2 mediates morphine-induced delayed cardioprotection via an ...
人参皂甙R(1;诱导型一氧化氮合酶;环加氧酶2;前列腺素E2;核因子一KB InhibitoryeffectofginsenosideRdoniNOSandCOX·-2expressioninLPS--stimu-- latedRA、v264.7cells YUYah—Hua.SHIZhuo,LIYah—Jie,BAOMtg—Yu,ZHAOLi—Hong,HAOCheng—Xin.BaichengMedicalCollege, ...
(iNOS), a small molecule that has various roles in cellular functions and acts via a cGMP-mediated signal transduction pathway. iNOS is both tumouricidal and bactericidal, has nitrosylase activity, and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2. It is regulated by...
SCEA-F significantly inhibited the productions of NO and PGE2 by inhibiting iNOS and COX-2 at their protein and gene levels. The production and the gene transcription of pro-inflammatory cytokines are also inhibited. The responsible molecular signaling for these inhibitory actions was found to be ...
COX-2免疫组化染色.同时用凝胶电泳迁移率(EMSA)的方法测定心肌组织NF-κB活性.结果:(1)糖尿病大鼠心肌组织NF-κB阳性表达细胞明显多于对照组;(2)EMSA方法显示,糖尿病大鼠心肌组织NF-κB表达强度明显高于对照组;(3)对照组大鼠心肌组织未见iNOS的表达,糖尿病大鼠见明显iNOS的表达;(4)对照组大鼠心肌组织偶见COX-2的...
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2. ...
242 104 0 0 2 0PDF下载摘要 目的检测iNOS、nNOS在急性CO中毒迟发性脑病中表达及其与海马神经元变性坏死的相关性分析,探索iNOS、nNOS在急性一氧化碳中毒迟发性脑病(delayed encephalopathy after acute carbon monoxide poisoning, DEACMP)发病中的作用。 方法选择成年雄性SD大鼠72只,随机(随机数字法)分为DEACMP组...