The small effect sizes we observe, across three parasite species, following experimental perturbations of the innate immune system may be explained by redundancy in a complex biological system or by incomplete (or inappropriate) data reporting for meta-analysis. Alternatively, ...
1The innate immune system The innateimmune systemis one of the two mainarmsof the body's defense system against pathogens. From an evolutionary perspective, it is older than theadaptive immune system, the second main branch of the immune system [1]. The major distinction between the two parts...
21. The Immune System Topic summary Created using AI The innate immune response is the body's first line of defense against pathogens, comprising three main components: chemical and physical barriers,cellintrinsic responses, and phagocytic cells. Pathogen-associated molecular patterns (PAMPs) are recog...
Immune memory has long been considered a function specific to adaptive immune systems; however, adaptive immune memory alone has not fully explained the mechanism by which vaccines exert their protective effects against nontarget pathogens. Recently, trained immunity, in which human monocytes vaccinated ...
It has been hypothesised that the regulation of human life histories is explained by the disposable soma theory, which postulates that investments in survi... PDRGJ Westendorp - 《Cesar L Escalante》 被引量: 0发表: 2004年 Activation and regulation of the innate immune system in response to Ure...
a balanced response is needed as part of a “goldilocks” just-right scenario. In this review, we aim to summarize the innate immune response to SARS-CoV-2 infection with regard to disease modulation and immune system evasion and determine how we might manipulate this response for therapeutic ...
Spreading depolarization (SD) is a complex event that induces significant cellular stress in the central nervous system, leading to a robust inflammatory response without causing cell death in healthy tissues which may be called as neuro-parainflammation
Z-RNA is a higher-energy, left-handed conformation of RNA, whose function has remained elusive. A growing body of work alludes to regulatory roles for Z-RNA in the immune response. Here, we review
These results indicate that during the nestling period there are no sexual differences in this component of the innate immune system. In addition, they suggest that there is little association between this component of innate immunity and the reproductive performance and physical condition during the ...
In this chapter, the recent development of the understanding of the innate immunity, mostly the origin and contribution of tissue-resident macrophages was explained. Interestingly, recently tissue-resident macrophages, major player of innate immunity are not derived from circulating monocyte, especially ...