Innate immune cells are white blood cells that mediate innate immunity and include basophils, dendritic cells, eosinophils, Langerhans cells, mast cells, monocytes and macrophages, neutrophils and NK cells. Fea
Multiple effector mechanisms of adaptive immunity ultimately rely on the clearance function of innate immune cells. Moreover, the products of the adaptive immune system will enhance the efficacy of innate immune responses. Thus, in vertebrates, innate and adaptive immunity act in a well-tuned ...
cells and factors [1]. Important representatives of the cells of the innate immune system aremononuclear phagocytes(monocytes, macrophages and dendritic cells), granulocytes (neutrophil,basophiland eosinophil), mast cells and NK cells. Soluble factors such as the complement system,defensins,lysozyme, ...
Innate immune cells have complex signalling pathways for sensing pathogens and initiating innate immune responses against infection. These pathways are tightly regulated at different levels, including by epigenetic regulators. In this Review, we discuss studies revealing the epigenetic mechanisms, as well ...
Innateimmunecells 固有免疫功能 Functionsofinnateimmune 第一节 固有免疫系统概述 Overviewofinnateimmunesystem Componentsoftheinnateimmunesystem -barriers-cells -humoralcomponents 一、屏障结构（Barriers)（一）物理屏障（Physicalbarriers)（二）解剖学屏障(Anatomicbarriers)（三）生物屏障(Biologicalbarriers)化学屏障 微...
and inflammatory responses, pyroptotic cell death and the recruitment of phagocytic cells. These innate responses are responsible for efficient destruction and clearance of invading pathogens and other molecular threats and instructing the development of an appropriate pathogen-specific adaptive immune respons...
ICE®(innate cell engager) molecules bring together the innate immune cell (NK cell or macrophage) and tumor cell by binding to the CD16A receptor on innate immune cells and a specific receptor on the tumor cells. Once this bridge is established, the immune cell is activated to release fac...
TheCellsoftheInnateImmuneSystem（一）、肥大细胞（mastcells）（二）、吞噬细胞（phagocytes）（三）、NK细胞（Naturalkillercells）（一）肥大细胞（mastcells）1、分布：呼吸道、消化道和皮肤等组织中的血管、淋巴管、腺导管导管和神经末梢周围。2、胞浆颗粒：含有炎症介质（组胺）和蛋白水解酶。3、表达高亲和力受体...
The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specializedchemical mediators(化学介质), calledcytokines(细胞因子) Activation o...
一、Innateimmunesystem •Innateimmunebarrier:skin-mucosalbarrier•Innateimmunemolecules：cytokines,complement,lysozyme,andsoon.•Innateimmunecells:phagocytes、NKcell、γδTcell、NKTcell、DC、B1cell&mastcell 1,barrier Skin-mucosalbarrierPhysicalbarrierChemicalbarrierBiologicalbarrierBloodbrain...