Selain itu, perkembangan teknologi seperti live draw SGP memungkinkan pemain untuk mendapatkan hasil keluaran secara real-time, meningkatkan keakuratan analisis mereka. Data berbasis waktu nyata ini memberikan manfaat tambahan bagi pemain yang ingin tetap up-to-date dengan informasi terbaru dan memper...
(1) Background: Acquired brain injury (ABI) or spinal cord injury (SCI) constitutes a severe life change for the entire family, often resulting in decreased quality of life (QoL) and increased caregiver burden. The objective of this study was to investig
One microgram of total RNA was reverse transcripted using a one-step RT Kit (Takara Bio, Shiga, Japan) and the resulting cDNA was used as a PCR template for determining the mRNA expression level using an SYBR-green quantitative PCR kit (Takara Bio, Shiga, Japan) by real-time quantitative ...
OGG1 expression rose continuously as reperfusion time increased, but there was no corresponding increase in its base repair activity. They also reported that OGG1 interferes with mitophagy by limiting PINK1 translocation to the mitochondria. Accordingly, OGG1 inhibition or knockdown alleviated renal IRI...
However, although the mortality rate in IFNAR−/− mice in the initial time points was lower (~20%), they evolved to a similar lethality as the wild-type mice even with liver histologic analyses showing no signs of necrosis 24 h after injury (Figure 7B,C). Moreover, significantly ...
International Journal of Molecular Sciences Article Endogenous Selenoprotein P, a Liver-Derived Secretory Protein, Mediates Myocardial Ischemia/Reperfusion Injury in Mice Hiroshi Chadani 1, Soichiro Usui 1,* ID , Oto Inoue 1, Takashi Kusayama 1, Shin-ichiro Takashima 1, Takeshi Kato 1, Hisayoshi ...
International Journal of Molecular Sciences Article Neuroprotection by Caffeine in Hyperoxia-Induced Neonatal Brain Injury Stefanie Endesfelder 1,*, Ulrike Weichelt 2, Evelyn Strauß 1, Anja Schlör 3, Marco Sifringer 4, Till Scheuer 1, Christoph Bührer 1 and Thomas Schmitz 1 1 Department ...
To this end, we combined high-throughput transcriptomics and proteomics and at two different time-points (7 days and 8 weeks) after SCI to capture consistent and persistent molecular changes post-SCI and to identify proteins with important bioactivity and drug-targeting potential. First, we ...
Furthermore, H2O2 induced TOPK phosphorylation in a time-dependent manner. Interestingly, TOPK inhibition aggravated the H2O2-induced oxidative stress injury in myocardiocytes, whereas overexpression relieved it. In addition, the ERK pathway was positively regulated by TOPK signaling. In conclusion, ...
International Journal of Molecular Sciences Article Protective Effect of Koumine, an Alkaloid from Gelsemium Sempervirens, on Injury Induced by H2O2 in IPEC-J2 Cells Zhihang Yuan 1,2, Zengenni Liang 3, Jine Yi 1,2, Xiaojun Chen 1,2, Rongfang Li 1,2, Yong Wu 1,2, Jing Wu 1,2,* ...