But now scientists at Massachusetts Institute of Technology, US, have developed injectable nanoparticles that, once inside the body, release insulin in response to glucose levels, mimicking pancreas activity for over a week. 年份: 2013 收藏 引用 批量引用 报错 分享 ...
But now scientists at Massachusetts Institute of Technology, US, have developed injectable nanoparticles that, once inside the body, release insulin in response to glucose levels, mimicking pancreas activity for over a week.Emma DoreyChemistry & Industry...
Electroceuticals, through the selective modulation of peripheral nerves near target organs, are promising for treating refractory diseases. However, the small sizes and the delicate nature of these nerves present challenges in simplifying the fixation an
To address the high local glucose levels in diabetic lesions over the long term, Metformin Hydrochloride (MH) is used. MH is a stable and efficient drug widely used for diabetes, enhancing insulin responsiveness and reducing hepatic gluconeogenesis. For sustainable delivery, MH is loaded into a se...
aspart, ns not significant, IDet Insulin detemir, IGlar insulin glargine, OD once daily, T1DM type 1 diabetes mellitus, T2DM type 2 diabetes mellitus patients with T2DM, IDegAsp can be administered either alone or with oral anti- diabetic medicinal products and in combination with bolus insulin...
Initially, GEP44 only had ahalf lifeof about an hour in the body, but thanks to an improved formulation, the researchers are hopeful that future treatments could be given as injections just once or twice a week. The team has filed for patents on the drug, and plan to conduct more advanc...
Statistical comparisons were made using a one-way ANOVA, and the false discovery rate (FDR) was controlled at 5% using the Benjamini, Krieger, and Yekutieli method. Each formulation yielded a high-quality hydrogel, and we observed consistent yield strain behavior once lipid content was increased ...
Once cells were confluent, we created in vitro wounds by scratching the cell layers with a consistent pipette, and filled the wound bed with Piezo, Non-Piezo, and control samples. Fig. 3b displays the fluorescent images of cells distribution in different groups at 0 h (when wounds were ...
We next evaluated the immune response to the composites. Inducible nitric oxide synthase (iNOS)+proinflammatory macrophages were mainly distributed around the implanted materials, and only a small number of these cells had infiltrated into the interior of the mECM and microspheres after 1 week, and ...
The dose may be increased to a maximum of 60 mg for patients who have not normalized growth hormone (GH) and/or age and sex adjusted insulin-like growth factor-1 (IGF-1) levels after 3 months of treatment with SIGNIFOR LAR at 40 mg and who tolerate this dose [seeADVERSE REACTIONSandCl...