Hemophilia is due to a gene carried in the X chromosome and is recessive to the normal. The X chromosome of the male comes from the mother and the Y chromosome from the father. Consequently, hemophilia in the male must be transmitted by the mother. Women rarely, if ever, have the ...
9. Hemophilia is a disease where the blood does not clot properly. The pedigree chart below shows the inheritance of this condition in a family. Determine the genotype of person 1. [1 mark] Deduce the genotype of the mother of person 2. [1 mark] If person 3 has a son, and the fath...
The special features of X-linked recessive inheritance are seen in the transmission of hemophilia A (Fig. 3-4). This is a blood disorder in which a vital clotting factor (factor VIII) is lacking, causing abnormally delayed clotting. Hemophilia exists almost exclusively in males, who receive th...
For the F2 generation, the law of segregation requires that each gamete receive either anRallele or anrallele along with either aYallele or ayallele. The law of independent assortment states that a gamete into which anrallele sorted would be equally likely to contain either aYallele or ayallele...
Some X-linked traits in humans are color blindness, muscular dystrophy, hemophilia, congenital deafness, spinal ataxia, ocular albinism, brown teeth, congenital cataract, retinitis pigmentosa, diabetes insipidus, etc. The X-linked inheritance for a particular gene in females may either be homozygous ...
Hemophilia A is the most widely recognized X-linked recessive disorder. It has affected the royal families of Europe because Queen Victoria was a carrier, and a number of her male descendants were affected. Figure 5.16 depicts a typical pedigree for an X-linked recessive trait that we’ll assu...
The patterns of genetic inheritance within families and the behavior of genes at the level of a population are of fundamental importance in the estimating the future risk of genetic diseases within families and in the general population. In this chapter, the common patterns of inheritance and the...
the phenotype of X-linked traits inherited from their mother, as they only inherit one X chromosome. On the other hand, females have two X chromosomes, so they may be carriers of X-linked traits without displaying the phenotype. Examples of X-linked diseases are hemophilia and color blindness...
The special features of X-linked recessive inheritance are seen in the transmission of hemophilia A (Fig. 3-4). This is a blood disorder in which a vital clotting factor (factor VIII) is lacking, causing abnormally delayed clotting. Hemophilia exists almost exclusively in males, who r...
What is hemophilia? How is it inherited? Make a pedigree to illustrate its pattern of inheritance. What is the difference between phenotype and genotype? What is the difference between a phenotype and a genotype? How can you find the number of pairs of alleles involved in polygenic inheritance...