Drug Interactions • Agents increasing serum potassium: Concomitant administration can lead to hyperkalemia (5.1, 7.1). • Lithium: Increased risk of lithium toxicity (7.2). • NSAIDs: May reduce the diuretic, natriuretic and antihypertensive effect of spironolactone (7.3). • Digoxin: Spirono...
Spironolactone acts both as a diuretic and as an antihypertensive drug by this mechanism. It may be given alone or with other diuretic agents that act more proximally in the renal tubule. 12.2 Pharmacodynamics Aldosterone antagonist activity: Increased levels of the mineralocorticoid, aldosterone, are...
They may differ from the information contained here. If you do not understand the instructions on the box, ask your doctor or pharmacist for help. Your doctor or pharmacist will tell you how many tablets you will need to take each day. This depends on your condition and whether or not you...
Review on Molecular Mechanism of Hypertensive Nephropathy. November 03, 2023 [MEDLINE Abstract] Drug Delivery for Ocular Allergy: Current Formulation Design Strategies and Future Perspectives. November 02, 2023 [MEDLINE Abstract] Silencing MFHAS1 Induces Pyroptosis via the JNK-activated NF-κB/Caspase1...
“The [BMJ] study showed prolonged use of medrogestone, medroxyprogesterone acetate, and promegestone was found to be associated with an increased risk of meningioma. No excess risk of meningioma was associated with the use of progesterone, dydrogesterone, or spironolactone, or the hormonal intraute...
Lo-Zumandimine contains 3 mg of the progestin DRSP which has anti-mineralocorticoid activity, including the potential for hyperkalemia in high-risk patients, comparable to a 25 mg dose of spironolactone. Lo-Zumandimine is contraindicated in patients with conditions that predispose to hyperkalemia (th...
7. DRUG INTERACTIONS 7.1 Agents Increasing Serum Potassium Concomitant use of olmesartan with other agents that block the renin-angiotensin system, potassium-sparing diuretics (e.g., spironolactone, triamterene, amiloride), potassium supplements, salt substitutes containing potassium or other drugs that ma...
Provides information on the drug applications for lithium carbonate approved by the U.S. Food and Drug Administration. History of lithium in psychiatry; Indication for the use of lithium carbonate; Toxic reactions related to serum lithium levels. DOI: 10.7326/0003-4819-73-2-291 年份: 1970 收藏...
Drospirenone, has a close chemical resemblance to spironolactone, a diuretic, which may be responsible for a number of Yaz’s unique side effects, particularly those affecting the kidneys. Over the course of a month, Yaz also provides patients with an increased hormone dose in comparison to ...
RU 58841:This is the mother of all topical anti androgens. RU58841 is made by the Roussel Corporation of France. This stuff shuts down DHT at the hair follicle like nothing else. One of the major problems has been that anti androgens such as Spironolactone and Flutamide taken orally might ...