In this work, we formulate binding affinity as a classification problem: classifying protein complexes as having low or high binding affinity. Thus, our dataset consists of examples of the form (ci, yi) whereciis a protein complex andyi ∈ {+1, −1} is its associated label indic...
The decrease in entropy therefore provides a quantitative measure of the information gained by observation of a system. If we adopt a scaled binary entropy SB = −k s i=1 pi log2 pi, the information gained by a binary decision is k, measured in the units of k. For a scaled entropy...