Reproduction studies were performed at doses up to 50 mg/kg/day in rats and 6 mg/kg/day in rabbits administered during organogenesis. These doses are approximately 8 (rat) and less than 2 (rabbit) times the maximum recommended human dose (MRHD – 60 mg) on an mg/m2 basis. These stu...
Ziprasidone capsules should be administered at an initial daily dose of 20 mg twice daily with food. In some patients, daily dosage may subsequently be adjusted on the basis of individual clinical status up to 80 mg twice daily. Dosage adjustments, if indicated, should generally occur at interva...
50 mg/mL CIIFor IM, SC orslow IV useDo not useif precipitated 1 mL Vial NDC 0641-6053-25 Rx only MeperidineHCl Injection, USP50 mg/mL CIIFor Intramuscular, Subcutaneousor slow Intravenous use 25 x 1 mL Single Dose Vials PRINCIPAL DISPLAY PANEL NDC 0641-6054-01 Rx only MeperidineHCl ...
60 mg is blue opaque/green opaque, size ‘1’ hard gelatin capsule filled with white to off-white pellets and imprinted with ‘X’ on blue opaque cap and ‘03’ on green opaque body with black ink.4. Contraindications The use of MAOIs intended to treat psychiatric disorders with duloxetine...
In a 105-week carcinogenicity study, malignant astrocytoma was seen in 3 of 50 male rats at 10 mg/kg/day (approximately 3 times the MRHD on a mg/m2 basis). There were no tumor findings in female mice or rats. Mutagenesis Cyclobenzaprine HCl was not mutagenic or clastogenic in the ...
However, when using maternal breastmilk data to estimate the daily and relative infant dose, the infant dose was 0.006 mg/kg/day, which is 1.3% of a weight-adjusted maternal dose of 10 mg every 6 hours. These estimates based on maternal breastmilk concentrations were corroborated by the ...
Drugs that have been shown, or that would be expected, to decrease plasma carbamazepine levels include cisplatin , doxorubicin HCl, felbamate, fosphenytoin, rifampin, phenobarbital, phenytoin, primidone, methsuximide, theophylline, aminophylline. Effect of Carbamazepine on Plasma Levels of Concomitant ...
After treatment induction and stabilization, the maintenance dose of buprenorphine and naloxone sublingual film is generally in the range of 4 mg/1 mg buprenorphine/naloxone to 24 mg/6 mg buprenorphine/naloxone per day depending on the individual patient and clinical response. The recommended target ...