The potential for future development of these novel influenza vaccine candidates is discussed from an industry perspective.Background Seasonal influenza outbreaks cause 3 to 5 million cases of severe illness and 290,000 to 650,000 respiratory deaths each year [1, 2]. The Orthomyxoviridae are a ...
However, in Singapore, vaccine uptake remains suboptimal relative to other routine childhood immunisations. Limited information exists regarding determinants of influenza and pneumococcal vaccine uptake in children. We estimated vaccine uptake and investigated factors associated with influenza and pneumococcal ...
vaccination status for the ACS cohort was not known. However, in the Netherlands individuals <60 years of age are only eligible for influenza vaccination if they have underlying health conditions, and assuming population-wide rates of influenza vaccine uptake in the Netherlands...
Thus, protective vaccines cannot be taken ahead of time to prevent influenza B because whether the vaccine provides immunity to the human body or not depends on how well the pandemic strain matches that of the vaccine. Protection provided by the vaccine is limited when the pandemic strain does ...
Introduction of a second clean day every month in live-poultry markets and the use of inactivated H5N1 vaccine on poultry farms in Hong Kong are further measures being taken to keep H5N1 out of live-poultry markets. What we now know about H5N1 in live-poultry markets illustrates the difficulty...
influenza; H5N1; H1N1; pandemic; vaccine; haemagglutinin (HA); neuraminidase (NA)1. Introduction While most people had anticipated the next pandemic virus to have a novel HA subtype of avian origin (such as H5), the sudden emergence in 2009 and the rapid global spread of swine-origin ...
is extremely important for sequence-based antigenicity quantification and vaccine strain selection; thus, it should always be considered as an essential factor in sequence-based predicting models. Current model only considers the presence or absence of theN-glycans at the HA but not the structure and...
Vaccination has been deliberately omitted from this study. The effectiveness and cost effectiveness of vaccination will depend crucially on the timing of the availability of the vaccine relative to the arrival of the pandemic in the community – vaccination cannot be plausibly modelled without considering...
combined with dispensing free of charge vaccine, on vaccination rate. The campaign was conducted by the Hospital Infection Control Team of the Czerniakowski Hospital in Warsaw, Poland, separately for physicians, nurses, and physiotherapists. Overall, 37 % of medical staff were vaccinated, including ...
L W AngJ CutterL JamesK T GohEpidemiol InfectFactors associated with influenza vaccine uptake in older adults living in the community in Singapore. ANG L W,CUTTER J,JAMES L,et al. Epidemiology and Infection . 2017Ang LW, Cutter J, James L, Goh KT. Factors associated with influenza ...