Still, studies show that when strains in the vaccine are a good match with the ones that are circulating, vaccinated individuals are 40% to 60% less likely to catch the flu than people who aren't vaccinated, according to the CDC. Additional resources Search for flu vaccines near you on V...
To combat this obstacle, novel methods of designing influenza vaccines and antivirals continue to improve the induction of cross-reactive immune responses that inhibit viral replication in order to tackle the genetic diversity inherent to influenza virus evolution. Historically, vaccine and antiviral ...
Vaccine 2012, 30, 4419–4434. [CrossRef] [PubMed] 57. Puryear, W.; Sawatzki, K.; Hill, N.; Foss, A.; Stone, J.J.; Doughty, L.; Walk, D.; Gilbert, K.; Murray, M.; Cox, E.; et al. Highly Pathogenic Avian Influenza A(H5N1) Virus Outbreak in New England Seals, United...
During vaccine selection, experts consider only data generated from the naïve ferret model for determination of recommended strains for currently administered human vaccines. However, the immune response in a naïve host, compared to a pre-immune individual, differs during subsequent vaccination and/...
It was hypothesized that the majority of alternative functional configurations (AFC) within the AIV HA1 can be represented by the pool of vaccine seed viruses currently in production because only a finite number of AFC are possible within each substructure of the molecule. Therefore, combinations ...
Article Historical H1N1 Influenza Virus Imprinting Increases Vaccine Protection by Influencing the Activity and Sustained Production of Antibodies Elicited at Vaccination in Ferrets Magen E. Francis 1, Mara McNeil 1, Nicholas J. Dawe 1, Mary K. Foley 1, Morgan L. King 1, Ted M. Ross 2 and ...