The death toll of this virus has been estimated to be between one and four million. • H3N2 serotype caused the Hong Kong influenza outbreak of 1968, which is estimated to have killed at least a million people between 1968 and 1969. This serotype is believed to have descended fr...
influenza had spread from southern Europe all the way to the northern European countries, and the infection subsequently reached the Americas. The actual death toll is unknown, but 8,000 deaths occurred in Rome alone.
The COVID-19 pandemic has taken a heavy toll on children, especially in terms of their mental health. For example, they are more likely to experience famil... D Isaacs - 《Journal of Paediatrics & Child Health》 被引量: 0发表: 2023年 Changes in epidemiology of patients visiting emergency...
Influenza takes a disproportionate toll on people over 65 years old, largely due to an age-related deterioration in immune function known as immune senescence.10 Immune senescence, a phenomenon associated even with healthy aging, is characterized by decreased antimicrobial defenses and disordered immune...
Article 02 August 2023 Human seasonal influenza under COVID-19 and the potential consequences of influenza lineage elimination Article Open access 31 March 2022 Cross-reactive immunity potentially drives global oscillation and opposed alternation patterns of seasonal influenza A viruses Article Open ...
Cell Death & Disease(2023) TRPV4 channel is involved in HSV-2 infection in human vaginal epithelial cells through triggering Ca2+ oscillation Ping Jiang Song-shan Li Shu-wen Liu Acta Pharmacologica Sinica(2023) EV-A71 induced IL-1β production in THP-1 macrophages is dependent on NLRP3, RIG...
are critical to such poor vaccine responses. Aging of the innate immune system is notable for a chronic inflammatory state that is associated with impaired functions of innate immune pattern recognition receptors such as the retinoic acid-induced gene-I (RIG-I) and Toll-like receptors (TLRs) [...
PD-1 programmed cell death protein-1 SARS severe acute respiratory syndrome SIRS Systemic Inflammatory Response Syndrome TIM-3 T-cell immunoglobulin domain and mucin domain protein-3 1. Introduction The emerging and reemerging respiratory virus infections pose a continuing threat to human life. Acute ...
L929 cells were plated and cultured overnight in the presence of the samples for analysis in serial dilutions. L929 cells were then infected with VSV and incubated for another 2 days. interferon levels were then evaluated by the extend of virus induced cell death compared with interferonalpha ...
Cell Death & Differentiation(2023) Apoptotic cell death in disease—Current understanding of the NCCD 2023 Ilio Vitale Federico Pietrocola Lorenzo Galluzzi Cell Death & Differentiation(2023) Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and ...