Comparative Severity of Influenza A and B Infections in Hospitalized Childreninfluenza Ainfluenza Bclinical severityhospitalizationinfluenza vaccinesBackgroundMattila, Janna-MaijaVuorinen, TyttiHeikkinen, TerhoTurku Univ Hosp Dept Pediat Turku FinlandThe Pediatric infectious disease journal...
Influenza A and B Viruses Influenza A Influenza A viruses are classified into subtypes based on two of their surface proteins, hemagglutinin (HA) and neuraminidase (NA). To date, 18 HA and 11 NA subtypes have been identified, though this includes two subtypes of bat influenza that,...
Pertussis (Tdap)b I Yes Yes No Inactivated Polio vaccine I Yes Yes No H. influenza type Bc I Yes Yes Yes S. pneumonia(conjugate vaccine) I Yes Yes No S. pneumonia(polysaccharide vaccine) I Yes Yes No Rabiesa,d I Yes Yes Yes Human papilloma virus (HPV) I Yes Yes No Varicella(live...
Since the 1970s influenza B has diverged into two lineages based on antigenicity, the Yamagata and Victoria lineages, with little or no serum cross-reactivity [4]. In contrast to the severity and epidemic potential of influenza A and B, influenza C infections induce only mild flu symptoms in...
The influenza pandemic that emerged in 2009 provided an unprecedented opportunity to study adaptation of a virus recently acquired from an animal source du... Ruth,A,Elderfield,... - 《Journal of Virology》 被引量: 61发表: 2014年 Changes in Severity of Influenza A(H1N1)pdm09 Infection from ...
Human infection with avian influenza A H7N9 virus: an assessment of clinical severity. Lancet 382, 138–145, doi: 10.1016/S0140-6736(13)61207-6 (2013). 4. Gao, H. N. et al. Clinical findings in 111 cases of influenza A (H7N9) virus infection. N Engl J Med 368, 2277–2285, doi...
The amino acid sequence of this cleavage site modulates tissue tropism and systemic spread, affect- ing disease severity (discussed below). The neuraminidase activity of NA is crucial for destroying the SA-containing receptors of the host and viral membranes, a process that is required for proper...
Conclusions Due to selection bias, the natural and experimental infections had limited symptom severity distributional overlap precluding valid, propensity score–adjusted comparison. Relative to the symptomatic naturally infected cases, where high aerosol shedders were found, experimental cases did not ...
but this seasonality is more variable in the tropics (see below). Two subtypes (A and B) have been described and may co-circulate, with one usually predominating in any given year. No obvious differences in disease severity or pathogenesis have been documented between these two subty...
2. A rapid surge in the number of cases in each affected area would occur very quickly, within weeks. The number of cases would vary with the severity of the outbreak, but there would be a sharp increase in demand for medical services. ...