Material & Methods: A total of 251 pharyangeal and nasal swabs from suspected cases of swineflu were processed by TaqMan real-time PCR (CDC protocol). Clinical co-relation with presenting sign and symptoms and analysis was done. Results: 36 (14%) were confirmed as positive. The clinical ...
The test can be negative (no flu infection) or positive for types A or B. If it is positive for type A, the person could have a conventional flu strain or a potentially more aggressive strain such as H1N1. Most of the rapid tests are based on PCR technology that identifies the genetic...
the NP gene of swine H1N1 influenza virus positive, and the HA gene of type A H1N1 influenza virus positive. Routine blood test revealed WBC count 6.69 × 109/L, GR% 78.1 %, LY% 12.7 %, MONO% 7 %, and HGB 118 g/L. Blood biochemistry ...
Thirty-nine patients were also positive by PCR for influenza A infection with 15 H1N1 and 5 H3N2 subtypes identified. Amongst the virus isolates, 30 H1N1 and 1 H3N2 influenza A subtypes with 26 influenza type B (Yamagata lineage) strains have been characterized. Two clades of the H1 viruses ...
andnasal obstructionand discharge. Elderly individuals may simply present with fever, lassitude, and confusion without any of the characteristic respiratory complaints. There may be a wide range of symptoms, but the presence of fever plus either sore throat or cough is predictive of positive culture...
As a positive control, MDCK cells showed a strong expression of both avian influenza receptors (α2,3-linked sialic acids) and human influenza receptors (α2,6-linked sialic acids) to ensure the reliability of the technology (Fig. 2d). Figure 2 No sialic acid residue, which is the ...
In the standard arm, one patient tested positive for influenza A, influenza B and RSV; two patients tested positive for influenza A and RSV. In the ROST arm, one patient tested positive for influenza A and RSV on the RPP, however tested positive for influenza A only on the ROST years ...
we found a strong positive correlation (Pearsonr = 0.94,p < 0.001) between IC80neutralizing activity against the two viruses, demonstrating that these viruses have equivalent neutralization sensitivities (Supplementary Fig.4d). Moreover, we found that the R4∆PB1 A/Switzerland/9715293/201...
In contrast, in post-1990 H9N2 subtype viruses, the predominant residue at position 103/106 is L/I found in 66% of total isolates, therefore demonstrating positive selection of these residues in poultry for this subtype (Figure 9). The H6N1 lineage has also selected 103L and 106I mutations ...
Host immunity has a dual role in governing the pace of virus evolution: innate immunity acts as a constraint on the generation of new virus variants, whereas adaptive immunity selects for immune escape mutants The acute nature of influenza virus infections and population-level epidemics provides lim...