Whilst this virus can infect humans and several other animal species, its virulence in humans is relatively benign compared to the previously described serotypes. This virus is highly pathogenic in many bird species and an outbreak of bird-adapted strain of H5N1 in 2004 in southeast Asi...
The aim of this paper is to compare the burden of influenza in the pandemic year 2009/10 with that in the year immediately after (2010/11) in England. We compared four measures of disease. There was a greater burden of severe illness in 2010/11 compared with 2009/10: more deaths (474...
Pandemic and post- pandemic influenza A (H1N1) seasons in a tertiary care university hospital-high rate of complications compared to previous influenza ... S Bauernfeind,T Bruennler,B Ehrenstein,... - 《Infection》 被引量: 11发表: 2013年 Severe 2009 H1N1 Influenza in Pregnant and Postpartum...
(a) ATAC-seq volcano plots showing genes with significant gain or loss (FDR < 0.05) of chromatin accessibility in AMs from day 30 IAV-infected mice as compared to those from uninfected (PBS) mice. (b) ATAC-seq signals for genes encoding MHC II (top), TNF (lower left), and CXCL...
Madin-Darby Canine Kidney (MDCK) cells are widely utilized as a substrate for influenza virus isolation and propagation due to the high yields of virus. Here we compared the conventional MDCK cell line, MDCK-SIAT1 and MDCK-London for vir... D Susu,AB David,S Patrick,... 被引量: 0发表...
Vaccines are the best available countermeasure against infection, but vaccine effectiveness is low compared with other viral vaccines, and the induced immune response is narrow and short-lived. Furthermore, inactivated influenza virus vaccines focus on the induction of systemic IgG responses but do not...
Compared to colloidal gold detection [11], the use of fluorescent microspheres for tracers is rapid, sensitive, and reliable [12,13,14]. Following lighting with an ordinary UV lamp or special equipment, reaction bands of the fluorescent microspheres for tracers can be observed with the naked ...
To determine if an ordered and repetitive display of an epitope promoted induction of superior antibody responses, we compared B-cell responses to an influenza A virus epitope that was either encoded as a transgene by an adenovirus (Ad) vector or expressed on the vector's surface. To this ...
) in 2016/2017: a difference of 0.66. Conversely, assuming the size of the previous season was the mean A/H3N2 season relative size (across all included countries and seasons), the effect of previous season size would only reduce predicted size by 0.06 (95% CI 0.01–0.12) compared to if...
(SAR1) were performed as controls. Immunofluorescence analysis showed that overexpression of SAR1-GTP reduced the size of viral inclusions, when compared to overexpression of GFP or SAR1, in a statistically significant manner (Fig.7a, b). The number of inclusions per μm2of cellular area and...