UC occurs more in males throughout lifetime. Significant sex differences are also seen in symptoms, disease severity, and extra-intestinal manifestations of IBD. Extra-intestinal manifestations tend to be observed more in female CD patients and male UC patients. The risk of colon cancer, the ...
Inflammatory Bowel Disease (IBD) is a term used to describe a group of conditions that cause chronic inflammation of the gut. IBD is further broken down into two primary conditions: Crohn’s disease and ulcerative colitis. Symptoms can appear and disappear unpredictably, with disease ‘flares’ ...
12]. NLRX1 was initially identified in the setting of infection as a repressor of the pro-inflammatory type-I interferon [13,14,15] and canonical NF-κB [16,17] immune
Researchers from the Wellcome Sanger Institute, the Hudson Institute of Medical Research, Australia, the University of Cambridge and collaborators, have discovered and named two new strains of bacteria in the microbiome of mice that cause inflammatory bowel disease (IBD) symptoms. The study, published...
In particular, 82 patients (49.40%) were aged more than 45 years. Sex distribution was 79 females (47.59%) and 87 males (52.41%). In 134 patients (80.7%) disease was considered clinically in remission, although 47% of all population had calprotectin levels higher than 250. Forty-five (...
In general, hospitalised patients with IBD tend to exhibit more severe inflammatory activity and more complicated disease than outpatients. Cytomegalovirus infection in hospitalised patients with IBD not only exacerbates gastrointestinal symptoms but also increases the risk of poor outcomes [7]. Therefore,...
Chronic Inflammation and Chronic Disease Chronic inflammation can be incredibly harmful to your body. Symptoms of chronic inflammation can vary from person to person and may include fatigue, chronic pain, headaches, migraines, muscles aches, joint pain, skin issues, brain fog, memory issues, insomnia...
However, the incidence of constipation is reduced in males; it is also reduced in the people being married or living with a partner, with high income–poverty ratio, ≥ high school education, smoking, drinking, BMI ≥ 25 kg/m2, physical activity ≥ 500 MET-min/week, diabetes...
Inflammatory Bowel Diseases (IBD) are the gastro-intestinal diseases of the current century. They are described by alternating periods of activity & remission. The assessment of severity is classically done by scoring systems for each disease which depend on patients’ symptoms, inflammatory markers, ...
Typically, joint symptoms tend to decrease and there is a predominance of cutaneous manifestations in young adults. Pathergy, nodulocystic acne, and pyoderma gangrenosum are frequent manifestations. The clinical presentation can be diverse, with variations in the disease described based on the presence...