The two main forms of inflammatory bowel disease (IBD) are Crohn's disease and ulcerative colitis. The past decade has seen substantial advances in our understanding of the pathogenesis of IBD, and in particular the complex interaction with functional alternations in the immune system. IBD is ...
Unravelling the pathogenesis of inflammatory bowel disease. Recently, substantial advances in the understanding of the molecular pathogenesis of inflammatory bowel disease (IBD) have been made owing to three related... RJ Xavier,DK Podolsky - 《Nature》 被引量: 7549发表: 2007年 Colorectal dysplasia ...
The role of the Hippo pathway in the pathogenesis of inflammatory bowel disease Article Open access 12 January 2021 References Xavier, R. J. & Podolsky, D. K. Unravelling the pathogenesis of inflammatory bowel disease. Nature 448, 427–434 (2007). ADS CAS PubMed Google Scholar Kaplan, ...
The dysfunction of the mucosal immune response is implicated in the pathogenesis of IBD. The balance between pro-inflammatory cytokines [tumor necrosis factor (TNF)-伪, interleukin (IL)-1b, IL-8, and IL-17A], anti-inflammatory cytokines (IL-4 and IL-13), and immunoregulatory ...
Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management, 9th edn. Philadelphia. Saunders/Elsevier, 2010.Search in Google Scholar [4] Knights D, Lassen KG, Xavier RJ. Advances in Inflammatory Bowel Disease Pathogenesis: Linking Host Genetics and the ...
Inflammatory bowel disease (IBD) is a chronic recurrent inflammatory disease of the intestine, including Crohn’s disease (CD) and ulcerative colitis (UC), whose etiology and pathogenesis have not been fully understood. Due to its prolonged course and chronic recurrence, IBD imposes a heavy economi...
Microbiota in Inflammatory Bowel Disease Pathogenesis and Therapy Inflammatory bowel disease (IBD), including ulcerative colitis, Crohn's disease, and unclassified IBD, continues to cause significant morbidity. While its ... DE Serban - 《Nutrition in Clinical Practice》 被引量: 47发表: 2015年 Linki...
Role of the gut microbiota in inflammatory bowel disease pathogenesis: What have we learnt in the past 10 years? Our understanding of the microbial involvement in inflammatory bowel disease(IBD) pathogenesis has increased exponentially over the past decade. The develo... Georgina L HoldMegan SmithCh...
摘要 Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is characterized by ch...展开更多 Inflammatory bowel disease(IBD),including Crohn’s disease and ulcerative colitis,is characterized by chronic relapsing intestinal inflammation.It has been a worldwide health-care...
The exact causes of inflammatory bowel disease (IBD) are not yet fully defined. From a vast body of literature, we know that the immune response has long been involved in the pathogenesis of IBD, including both ul- cerative colitis and Crohn's disease. A variety of specific alterations can...