Chung's research into ADAR1 persisted when she launched her own research lab at Columbia in 2019. She wanted to find out why the symptoms of AGS were mostly in the brain, when RNA is found throughout the body. If mutations in ADAR1 make the immune system recognize RNA in the brain and...
DEMENTIASYMPTOMSALZHEIMER'S diseaseThe article offers information on the strong link between neuroinflammation, measured by activated microglia levels (the brain's immune cells), and neuropsychiatric symptoms such as irritability, agitation, and nighttime disturbances in individuals with dem...
Methods: To investigate the pathway from inflammation to depression, we assessed serum levels of 3 inflammatory markers (tumor necrosis factor [TNF]‐alpha, interleukin [IL]‐6, and C‐reactive protein [CRP]), neural response during a reward fMRI task, and depressive symptoms using the Center ...
Previous studies showed that brain death negatively affects the immunological and inflammatory status of both liver and kidney. Since the intestine is increasingly used as a donor organ and no information on effects of brain death on small intestine is available we performed this study....
This review is mainly focused on the contribution of inflammation to depression. We first briefly introduce the inflammatory biomarkers of depression, then discuss the sources of cytokines in the brain, and finally describe the neuroimmunological mechanisms underlying the association between inflammation ...
be needed to fully realize the promise of anti-inflammatory therapy. While anti-inflammatory therapy may slow progression of some diseases, it may be necessary to begin taking anti-inflammatory agents long before symptoms appear, in order to prevent or reverse the ravages of neurodegenerative ...
In recent years, some new processes have been proposed to explain how alcohol may influence behavior, psychological symptoms and alcohol seeking in alcohol-dependent subjects. In addition to its important effect on brain and neurotransmitters equilibrium
Using a research model made up of humanbrain cells, the researchers from King's Institute of Psychiatry, Psychology & Neuroscience (IoPPN) examined the effects of a protein (interferon-alpha - IFN-α), which is able to activate the immune system and ultimately to induce depressive symptoms in...
Fatigue and inflammation : a psychoneuroimmunological approach o chronic fatigueChronic Fatigue Syndrome (CFS) is characterised by severe fatigue, endured for at least six months, together with symptoms including impaired cognitive function, ... ...
Keto Diet May Ease Multiple Sclerosis Symptoms New research suggests the ketogenic diet could help manage multiple sclerosis (MS) by promoting the production of beneficial compounds in the gut. In a study, mice on a keto diet produced the ketone body β-hydroxybutyrate (βHB), which worked with...