joint pain after a long workout, redness and swelling after a bee sting. these are examples of acute inflammation, or inflammation specific to one area of the body. now we're learning much more about another kind of inflammation - chronic inflammation. and your level of chronic inflammation m...
"There is such a thing as 'healthy' inflammation, meaning inflammation that allows the tissue to grow and has overall benefits to the tissue itself and the whole body," said Dr. Philipp Scherer, Director of the Touchstone Center for Diabetes Research and Professor of Internal Medicine and Cell...
longevity, and positive health outcomes. Testosterone exerts its effects by binding to the androgen receptor, which is expressed in numerous tissues throughout the body. Significant research has been conducted on the impact of this steroid hormone on skeletal, muscle ...
we used theAng+/+Con,Ang+/+Inf,Ang–/–Con, andAng–/–Inf models, as generated above, mated these mice with normal females, and then examined the metabolic parameters of the resulting progeny (Fig.2c, Supplementary Tab.2). The body weight ofAng+/+Inf F1 male mice showed a slight...
the reaction is actually the body’s natural allergic response to an infection in the connective tissues. This battle is the cause of the inflammation, pain, and disfiguring effects of RA since the disease agent is connected to the cell by various forms of comingling of foreign and host DNA...
Purpose: To examine the relationships between three measures of body fat—body mass index (BMI), waist circumference (WC), and total body fat percent—and markers of inflammation around dental implants in stable periodontal maintenance patients. Materials and Methods: Seventy-three subjects were enrol...
Macrophages are mononuclear phagocytes (MNPs) that are found in all tissues of the body. In the gut, macrophages reside in all layers of the small intestine and colon; the lamina propria, muscularis externa, and serosa. Macrophages in the muscularis and serosa interact with enteric neurons to...
The recruitment, accumulation, and activation of pro-inflammatory macrophages in metabolic tissues is the ultimate driver of this chronic low-grade inflammation. While the macrophage is the major effector cell type, other types of immune cells participate in these inflammatory processes. This review ...
Are there different forms or stages of senescent cells that exert distinct physiological effects? Does senescence have any yet new functions to the cells or tissues? To our knowledge, there are still many open questions that await answers. ...
Inflammatory responses that fail to regulate themselves become chronic and contribute to the continuation of the “disease” condition in the body; conditions of chronic inflammation include NCDs (cancer, CVD, diabetes, obesity, autoimmune diseases). Clinical inflammation: • Based on whether the indi...