The ‘enthesis organ’, a concept termed by McGonagle and Benjamin, includes structures apart from the anatomical insertion site itself, such as tendon,periosteum, bursa,fibrocartilage, and bone attachment [25]. The enthesis organ is important for dissipating stress from repetitive forces, and th...
Rhus Tox is a physician’s first choice of prescription in cases of joint pain. It is prescribed when the joint pains are the most severe during rest and also on initial movement. However, it gets better after continuous movement. Although there are a number of other medicines that treat th...
A small amount of synovial tissue was taken from the lateral and medial sides of the meniscus and the suprapatellar bursa region (the synovium sampled was the part that needed cleaning during surgery). The samples were preserved in EP tubes and stored at -80 °C. The study adhered to ...
Malignant neoplasms are a well-recognized global public health concern, with significant impacts on human health and quality of life. The interplay between tumors and autoimmune rheumatic diseases is complex, and the resulting tumor-associated rheumatic diseases represent a rare and intricate group of c...
react to a long-term, low-dose antibiotic treatment in such a short amount of time. Some conditions may require years. When the treatment is discontinued, a relapse occurs. These antibiotics are so effective in suppressing mycoplasmas that a reaction called the Jarisch-Herxheimer effect develops...
The role of inflammation in tendinopathy has been highly debated. Initially, researchers believed that inflammation was the primary pathological change following a tendon injury and that inflammation could lead to pain and functional impairment. During this period, the term “tendonitis” was generally ...
The term Tb may be a misnomer given that three of the cardinal symptoms of inflammation: warmth, erythema and swelling are rarely seen in these patients. Could use of US help us better understand Tb? Objectives To identify how commonly US and PD US changes suggestive of Trochanteric bursa ...
Cell-free DNA (cfDNA) released from damaged or dead cells can activate DNA sensors that exacerbate the pathogenesis of rheumatoid arthritis (RA). Here we show that ~40 nm cationic nanoparticles (cNP) can scavenge cfDNA derived from RA patients and inh
1. Introduction RA is a systemic autoimmune disease, occurring more commonly in women. It is prevalent in approximately 0.5–1% of the population [1–3]. The disease is characterized by persistent synovitis, which causes the destruction of cartilage and bone, and it even- tually leads to the...