Smooth muscle 22 alpha (SM22α), an important cytoskeleton-associated protein, is required for maintaining the contractile phenotype of VSMCs and is a sensitive and specific marker for identifying the dedifferentiation and phenotypic switching of VSMCs.36,37,38Recent studies from us and others hav...
improve the marker’s current prognostic capabilities. Therefore, we performed a heritability analysis in a sample of British twins to estimate the genetic contribution to suPAR levels for the first time. We then performed a GWAS on suPAR levels in a general Icelandic population cohort and in a ...
When a healthy person gets a cut or develops an infection, their immune system triggers inflammation. That signals blood vessels to enlarge around the injury, and white blood cells to rush in and repair the damage. When the injury or infection heals, the inflammation stops....
Generic marker of inflammation, such as complete blood count (CBC), C reactive protein (CRP) and Eritrocyte Sedimentation Rate (ESR) were widely used in the past for management of IBD patients [125], despite their low sensitivity and specificity [126]. Currently, it has been described an ...
Low magnesium is linked to high levels ofpro-inflammatory markersin humans. Lion’s Mane Mushroom You can eat lion’s mane mushroom (Hericium erinaceus) if you can find it in a market, but most often it’s taken as a supplement.
The SII is a novel marker that combines peripheral blood lymphocyte, neutrophil, and platelet counts and is linked to inflammation [31]. Previous studies have highlighted SII's high prognostic value in cancer patients, as well as its significance in predicting POP in lung cancer patients [32, ...
Atherosclerosis has been extensively linked to vascular inflammation. TRT has been significantly shown to reduce pro-inflammatory markers such as TNFα and IL-1β. An increase in the anti-inflammatory marker IL-10 was noted to correlate with a significant reduction in total cholesterol (Malkin et ...
(neutrophil marker) and citrulline histone H3. Using co-staining with the platelet marker CD41, colocalisation of citrullinated histone H3 positive signals were seen with platelets in the cavernoma in the cerebellum of theCcm3iECKOmice, mainly close to the endothelium (Fig.7C). Neutrophil–...
A significant LOD score for all animals was observed at the marker D1Mit305 (LOD, 5.7; fig. 3A) when an additive model was used, with the females displaying strong linkage (LOD, 5.3) whereas the males produced virtually no linkage across this region when the same model was used (LOD,...
The neuroinflammation marker translocator protein is not elevated in individuals with mild-to-moderate depression: a [(1)(1)C]PBR28 PET study. Brain Behav Immun 33: 131–138. CAS PubMed PubMed Central Google Scholar Hardingham GE (2009). Coupling of the NMDA receptor to neuroprotective and...