Doctors at the North Shore-LIJ Health System have discovered that increased inflammation in the prostate may predict reduced risk for prostate cancer. The findings are published online in Cancer. Prostate cancer is one of the most common cancers in men, with an estimated 240,000 new cases ...
Chronic inflammation in the prostate, seen as infiltration of inflammatory cells into the prostate gland in histological samples, affects approximately half the male population without indication of prostate disease, and is almost ubiquitous in patients diagnosed with benign prost...
E-cadherin immunostaining was inversely associated with age and inflammation, while stromal COX-2 immunostaining was positively associated with age and inflammation in the prostate. These findings suggest that the prostate epithelial barrier is altered and inflammation is increased with age in the ...
In the United States and in “Westernized” countries, the prevalence of both prostate cancer and prostate inflammation is very high, indicating that the two pathologies could be causally related. Indeed, chronic inflammation is now regarded as an “enabling” characteristic of human cancer. Prostate...
Kopp TI, Friis S, Christensen J, Tjonneland A and Vogel U. Polymorphisms in genes related to inflammation, NSAID use, and the risk of prostate cancer among Danish men. Cancer Genet 2013; 206: 266-278.Kopp TI, Friis S, Christensen J, Tjonneland A, Vogel U. Polymorphisms in genes ...
Objectives: To investigate associations of chronic inflammatory infiltrate (CII) with prostate cancer (PCa) risk and the number of positive cores in patients elected to a first set of biopsies. Materials and methods: Excluding criteria were as follows: active surveillance, prostate specific antigen (...
Prostate is an immune-competent organ normally populated by inflammatory cells. Prostatic inflammation origincan be multi-factorial and there are some emerging evidences on its possible role as a factor involved in prostatecancer (PC) pathogenesis and progression.This review critically analyzes the role...
Improvements in quality of life, antitumor immune responses, and inflammation could be resulting benefits of the incorporation of regular yoga practice in the lives of men with prostate cancer who are undergoing prostatectomy.
The findings of enavatuzumab-induced chemokines warrant further evaluation in clinical studies as potential biomarkers for such activity. The paper by M. Janiczek et al. presents a systematic review on immunotherapy as a promising treatment for prostate cancer. The authors summarize the recent ...
Prostate cancer is one of the most common cancers among men in the U.S. For many patients, hormone therapy is a treatment option. This type of therapy, also called androgen deprivation therapy (ADT), reduces the level of testosterone and other androgens