During the periparturient phase, cows are typically in an inflammation-like condition, and it has been suggested that inflammation associated with the development of stress of the endoplasmic reticulum (ER) in the liver contributes to the development of fatty liver syndrome and ketosis. In the pr...
Previous studies showed that brain death negatively affects the immunological and inflammatory status of both liver and kidney. Since the intestine is increasingly used as a donor organ and no information on effects of brain death on small intestine is available we performed this study....
et al. The Nlrp3 inflammasome suppresses colorectal cancer metastatic growth in the liver by promoting natural killer cell tumoricidal activity. Immunity 43, 751–763 (2015). CAS PubMed Google Scholar Bruchard, M. et al. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor ...
a"In particular, fat in the liver interferes with its function and insulin sensitivity," Katz said. This starts a domino effect, he explained. "Insensitivity to insulin causes the pancreas to compensate by raising insulin output. Higher insulin levels affect other hormones in a cascade that cause...
Although liver disease is a major complication of parenteral nutrition (PN) for intestinal failure (IF), its pathogenesis remains unclear. We investigated potential molecular mechanisms of liver injury in pediatric onset IF.Liver expression of canalicular phospholipid (ABCB4), bile acid (ABCB11), an...
Methylprednisolone Therapy in Deceased Donors Reduces Inflammation in the Donor Liver and Improves Outcome After Liver Transplantation: A Prospective Rando... Methylprednisolone therapy in deceased donors reduces inflammation in the donor liver and improves outcome after liver transplan- tation: a prospective...
Fatty liver disease has become a health problem related to metabolic syndrome worldwide, although its molecular pathogenesis requires further study. It is also unclear whether advanced fibrosis of steatohepatitis will regress when diet is controlled. The
During this process of regeneration, epithelial and non-parenchymal cells respond in a tightly coordinated fashion. Recent studies have described the interaction between inflammatory cells and a number of other cell types in the liver. In particular, macrophages can support biliary regeneration, ...
Inflammation accompanies obesity and its comorbiditiestype 2 diabetes, non-alcoholic fatty liver disease and atherosclerosis, among othersand may contribut... ME Kotas,MC Gorecki,MP Gillum - 《Adipocyte》 被引量: 84发表: 2013年 Obesity and the development of type 2 diabetes: the effects of fatty...
Figure 1. Chronic tissue inflammation in obesity In normal lean conditions, tissue macrophages in the liver, adipose tissue, pancreatic islets, intestine, and muscle generally display an anti-inflammatory M2-like (blue) polarization state. Obesity induces monocyte recruitment into the tissue and residen...