Circadian rhythm disruption impairs tissue homeostasis and exacerbates chronic inflammation in the intestine.doi:10.1096/fj.201700141RRPagel, RenéB?r, FlorianSchr?der, TorstenSünderhauf, AnnikaKünstner, AxelIbrahim, Saleh M.Autenrieth, Stella E....
RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook gastroenteritis (redirected fromInflammation of intestine) Thesaurus Medical Encyclopedia gas·tro·en·ter·i·tis (găs′trō-ĕn′tə-rī′tĭs) n.
Insulin-like growth factor-1 endues monocytes with immune suppressive ability to inhibit inflammation in the intestine The pathogenesis of some chronic inflammation such as inflammatory bowel disease is unclear. Insulin-like growth factor-1 (IGF1) has active immune regulatory capability. This study aim...
The growing realization that chronic inflammation is crucial in many diseases opens new avenues for treatment. EMBO Rep. 13, 968–970 (2012). CAS PubMed PubMed Central Google Scholar Garrett, W. S., Gordon, J. I. & Glimcher, L. H. Homeostasis and inflammation in the intestine. Cell ...
et al. STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing. J. Exp. Med. 206, 1465–1472 (2009). Article CAS PubMed PubMed Central Google Scholar Huber, S. et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. ...
The mechanism of the recovery of immune inflammation in the intestine remains to be investigated. The calcitonin-related protein (CGRP; neuropeptide) has immune regulatory capacity. We observed that lower levels of CGRP were found in the colon biopsies of UC patients. CGRP were negatively correlated...
Topicality of interrelation between intestine infections, inflammation diseases of intestine and autoimmune processes is widely discussed in scientific literature of recent years. Thereby a review of literature on the designated aspect of the problem is dedicated to the analysis of interconnection between ...
The laminin-511 (α5β1y1, key element of the extracellular matrix, mediates the epithelialmesenchymal interactions controlling the intestinal development and the cell renewal in the mature organ. A deregulation of the mechanisms implied in the homeostasis is obvious in inflammatory bowel diseases (IBD...
An improved understanding of the regulatory mechanisms that control epithelial claudin proteins will provide strategies to strengthen the epithelial barrier function and restore mucosal homeostasis in inflammatory disorders. 展开 关键词: epithelium intestine mucosal barrier tight junction claudins inflammation ...
In the intestine, ILC3srepresent an early dominant source of IL-22, which is critical for coordinating barrier maintenance at steady state and during bacterial infection4,5. While ILC3 activation signals are characterized4,5,6,7, the spatiotemporal regulation of intestinal ILC3 responses is ...